The AKT/mTOR pathway mediates neuronal protective effects of erythropoietin in sepsis (Q47976704)

7 February 2018

title

The AKT/mTOR pathway mediates neuronal protective effects of erythropoietin in sepsis (English)

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7 February 2018

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Guo-Bin Wang

1

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7 February 2018

Yun-Lan Ni

series ordinal

2

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7 February 2018

Xin-Ping Zhou

series ordinal

3

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7 February 2018

Wei-Fang Zhang

series ordinal

4

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7 February 2018

publication date

22 September 2013

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7 February 2018

Molecular and Cellular Biochemistry

published in

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7 February 2018

volume

385

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7 February 2018

issue

1-2

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7 February 2018

page(s)

125-132

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7 February 2018

Sepsis-associated encephalopathy and its differential diagnosis

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Mitochondrial respiratory chain and creatine kinase activities in rat brain after sepsis induced by cecal ligation and perforation

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Sepsis induces brain mitochondrial dysfunction

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NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits

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Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death

21 January 2018

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Localization of specific erythropoietin binding sites in defined areas of the mouse brain

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Recent trends in erythropoietin-mediated neuroprotection

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Erythropoietin improves skeletal muscle microcirculation and tissue bioenergetics in a mouse sepsis model

21 January 2018

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Erythropoietin attenuates lipopolysaccharide-induced white matter injury in the neonatal rat brain.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11010-013-1821-5

AKT/PKB signaling: navigating downstream

21 January 2018

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mTOR signaling in growth control and disease

21 January 2018

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Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway

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Culturing hippocampal neurons

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Treatment with N-acetylcysteine plus deferoxamine protects rats against oxidative stress and improves survival in sepsis

21 January 2018

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In vivo evidence that erythropoietin protects neurons from ischemic damage

21 January 2018

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Lower isoflurane concentration affects spatial learning and neurodegeneration in adult mice compared with higher concentrations

21 January 2018

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Sepsis-associated delirium

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Erythropoietin in the brain: can the promise to protect be fulfilled?

21 January 2018

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Exogenous erythropoietin provides neuroprotection of grafted dopamine neurons in a rodent model of Parkinson's disease.

21 January 2018

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Brain erythropoietin receptor expression in Alzheimer disease and mild cognitive impairment

21 January 2018

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A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity

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Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promises

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PKB and the mitochondria: AKTing on apoptosis

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PI3K/Akt and apoptosis: size matters

21 January 2018

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Akt regulates skeletal development through GSK3, mTOR, and FoxOs.

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An evolutionarily conserved Rit GTPase-p38 MAPK signaling pathway mediates oxidative stress resistance

21 January 2018

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Nicotinamide attenuates the ischemic brain injury-induced decrease of Akt activation and Bad phosphorylation.

21 January 2018

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Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

21 January 2018

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The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

21 January 2018

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The role of Akt-GSK-3beta signaling and synaptic strength in phencyclidine-induced neurodegeneration

21 January 2018

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Therapeutic effects of erythropoietin in murine models of endotoxin shock

21 January 2018

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12 December 2020

Late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants

1 reference

12 December 2020

Protein kinase B (c-Akt), phosphatidylinositol 3-kinase, and STAT5 are activated by erythropoietin (EPO) in HCD57 erythroid cells but are constitutively active in an EPO-independent, apoptosis-resistant subclone (HCD57-SREI cells).

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12 December 2020

Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation

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12 December 2020

Erythropoietin ameliorates renal dysfunction during endotoxaemia

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12 December 2020

Erythropoietin attenuates lipopolysaccharide-induced splenic and thymic apoptosis in rats

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12 December 2020

Erythropoietin therapy for acute stroke is both safe and beneficial

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12 December 2020

Anti-erythropoietin receptor monoclonal antibody: epitope mapping, quantification of the soluble receptor, and detection of the solubilized transmembrane receptor and the receptor-expressing cells

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12 December 2020

10.1007/S11010-013-1821-5

Identifiers

DOI

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7 February 2018

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7 February 2018