Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis. (Q47985451)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

L. Darryl Quarles

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Zhou-Sheng Xiao

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

language of work or name

English

0 references

publication date

7 March 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

25 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

20307-20313

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

25 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Expression and function of a stem cell promoter for the murine CBFalpha2 gene: distinct roles and regulation in natural killer and T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Causal relationship between the loss of RUNX3 expression and gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Regulation of chondrocyte differentiation by Cbfa1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Expression of the Runt domain-encoding PEBP2 alpha genes in T cells during thymic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Isolation and characterization of the distal promoter region of mouse Cbfa1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Cbfa1 isoforms exert functional differences in osteoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Rescue of the skeletal phenotype in CasR-deficient mice by transfer onto the Gcm2 null background

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

IRES-dependent translational control of Cbfa1/Runx2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Distinct requirements for Ras oncogenesis in human versus mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Characterization of the upstream mouse Cbfa1/Runx2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Cbfa1 is a positive regulatory factor in chondrocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Maturational disturbance of chondrocytes in Cbfa1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Activation of Peroxisome Proliferator-activated Receptor-γ Inhibits the Runx2-mediated Transcription of Osteocalcin in Osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Physical interaction of the activator protein-1 factors c-Fos and c-Jun with Cbfa1 for collagenase-3 promoter activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Induction of Osteoclast Differentiation by Runx2 through Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Osteoprotegerin Regulation and Partial Rescue of Osteoclastogenesis in Runx2–/– Mice by RANKL Transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Differential expression patterns of Runx2 isoforms in cranial suture morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Expression of the PEBP2alphaA/AML3/CBFA1 gene is regulated by BMP4/7 heterodimer and its overexpression suppresses type I collagen and osteocalcin gene expression in osteoblastic and nonosteoblastic mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

A PEBP2 alpha/AML-1-related factor increases osteocalcin promoter activity through its binding to an osteoblast-specific cis-acting element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Phosphate provides an extracellular signal that drives nuclear export of Runx2/Cbfa1 in bone cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

MAPK pathways activate and phosphorylate the osteoblast-specific transcription factor, Cbfa1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Runx2 deficiency in chondrocytes causes adipogenic changes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Runx3 is essential for the target-specific axon pathfinding of trkc-expressing dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Genomic organization, expression of the human CBFA1 gene, and evidence for an alternative splicing event affecting protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

Transcriptional mechanisms in osteoblast differentiation and bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401109200

21 January 2018

Identifiers

DOI

10.1074/JBC.M401109200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15007057%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference