The short isoform of PML-RARα activates the NRF2/HO-1 pathway through a direct interaction with NRF2. (Q47990678)

7 February 2018

title

The short isoform of PML-RARα activates the NRF2/HO-1 pathway through a direct interaction with NRF2. (English)

1 reference

7 February 2018

main subject

Promyelocytic leukemia

1 reference

Retinoic acid receptor, alpha

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Yulong Li

1

1 reference

7 February 2018

Hongyan Wang

2

1 reference

7 February 2018

Xiu Jun Wang

3

1 reference

7 February 2018

Xiuwen Tang

4

1 reference

7 February 2018

language of work or name

English

0 references

publication date

4 August 2017

1 reference

7 February 2018

published in

FEBS Letters

1 reference

7 February 2018

volume

591

1 reference

7 February 2018

issue

18

1 reference

7 February 2018

page(s)

2859-2868

1 reference

7 February 2018

Molecular basis of the Keap1-Nrf2 system.

cites work

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Modulation of NRF2 signaling pathway by nuclear receptors: implications for cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Rexinoid inhibits Nrf2-mediated transcription through retinoid X receptor alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Curing APL through PML/RARA degradation by As2O3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

The PML-retinoic acid receptor alpha translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

PML/RARalpha targets promoter regions containing PU.1 consensus and RARE half sites in acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Trafficking of the transcription factor Nrf2 to promyelocytic leukemia-nuclear bodies: implications for degradation of NRF2 in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Oxaliplatin activates the Keap1/Nrf2 antioxidant system conferring protection against the cytotoxicity of anticancer drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Methylated arsenic metabolites bind to PML protein but do not induce cellular differentiation and PML-RARα protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

RXRα inhibits the NRF2-ARE signaling pathway through a direct interaction with the Neh7 domain of NRF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Luteolin inhibits Nrf2 leading to negative regulation of the Nrf2/ARE pathway and sensitization of human lung carcinoma A549 cells to therapeutic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Cell-cycle regulation and dynamics of cytoplasmic compartments containing the promyelocytic leukemia protein and nucleoporins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Production and purification of lentiviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Missense mutations in PML-RARA are critical for the lack of responsiveness to arsenic trioxide treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

The PML domain of PML-RARα blocks senescence to promote leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Retinoic acid signaling in cancer: The parable of acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Acute promyelocytic leukaemia: novel insights into the mechanisms of cure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Regulation of heme oxygenase-1 gene transcription: recent advances and highlights from the International Conference (Uppsala, 2003) on Heme Oxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

HO-1 underlies resistance of AML cells to TNF-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

Nrf2 activation ameliorates cytotoxic effects of arsenic trioxide in acute promyelocytic leukemia cells through increased glutathione levels and arsenic efflux from cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1873-3468.12779

21 January 2018

Identifiers

DOI

10.1002/1873-3468.12779

1 reference

7 February 2018

PubMed ID

28777872

1 reference

7 February 2018