SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development (Q47992177)

7 February 2018

title

SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development (English)

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7 February 2018

11

R A Flavell

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7 February 2018

Roger John Davis

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object named as

R J Davis

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7 February 2018

author name string

W Swat

1

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7 February 2018

K Fujikawa

2

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7 February 2018

S Ganiatsas

3

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7 February 2018

D Yang

4

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7 February 2018

R J Xavier

5

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7 February 2018

N L Harris

6

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7 February 2018

L Davidson

7

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7 February 2018

R Ferrini

8

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7 February 2018

M A Labow

10

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7 February 2018

L I Zon

12

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7 February 2018

F W Alt

13

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7 February 2018

language of work or name

English

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publication date

1 May 1998

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7 February 2018

published in

Immunity

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7 February 2018

volume

8

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7 February 2018

issue

5

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7 February 2018

page(s)

625-634

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7 February 2018

Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene

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Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.

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Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog

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Thymocyte development is normal in CTLA-4-deficient mice

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7 January 2021

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

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RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

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Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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7 January 2021

Apoptosis: does stress kill?

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7 January 2021

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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7 January 2021

MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

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7 January 2021

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

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7 January 2021

Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway

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7 January 2021

Involvement of stress-activated protein kinase and p38 mitogen-activated protein kinase in mIgM-induced apoptosis of human B lymphocytes

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7 January 2021

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

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7 January 2021

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

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7 January 2021

MKK7 is a stress-activated mitogen-activated protein kinase kinase functionally related to hemipterous.

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7 January 2021

Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity

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7 January 2021

Novel components of mammalian stress-activated protein kinase cascades

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7 January 2021

Protein kinase cascades activated by stress and inflammatory cytokines

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7 January 2021

Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis

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7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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7 January 2021

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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7 January 2021

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

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7 January 2021

Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population

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7 January 2021

Defective activation and survival of T cells lacking the Ets-1 transcription factor

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7 January 2021

Fas and Fas ligand: a death factor and its receptor.

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7 January 2021

Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

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7 January 2021

Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.

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7 January 2021

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

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7 January 2021

Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice

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7 January 2021

AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

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7 January 2021

Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and -4

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7 January 2021

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

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7 January 2021

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

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7 January 2021

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

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7 January 2021

Mitogen-activated protein kinase cascades and regulation of gene expression

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7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

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7 January 2021

IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice.

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7 January 2021

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

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7 January 2021

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

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7 January 2021

Regulation of transcription by MAP kinase cascades

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7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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7 January 2021

Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice

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7 January 2021

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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7 January 2021

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

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7 January 2021

Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase

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7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

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7 January 2021

Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980567-1

7 January 2021

Daxx, a novel Fas-binding protein that activates JNK and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980567-1

7 January 2021

The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980567-1

7 January 2021

10.1016/S1074-7613(00)80567-1

Identifiers

DOI

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7 February 2018

PubMed ID

9620683

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7 February 2018