Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors. (Q47992225)

7 February 2018

title

Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors. (English)

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7 February 2018

author name string

Sarukhan A

1

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7 February 2018

Garcia C

2

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7 February 2018

Lanoue A

3

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7 February 2018

von Boehmer H

4

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7 February 2018

language of work or name

English

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publication date

1 May 1998

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7 February 2018

published in

Immunity

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7 February 2018

volume

8

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7 February 2018

issue

5

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7 February 2018

page(s)

563-570

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7 February 2018

Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor beta locus.

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7 January 2021

Checkpoints in the progression of autoimmune disease: lessons from diabetes models

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7 January 2021

T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous α- and β-genes

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7 January 2021

Exclusion and inclusion of α and β T cell receptor alleles

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7 January 2021

Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo

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7 January 2021

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire

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7 January 2021

A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes.

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7 January 2021

On the various manifestations of spontaneous autoimmune diabetes in rodent models

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7 January 2021

Isolation of leukocytes infiltrating the islets of Langerhans of diabetes-prone mice for flow cytometric analysis

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7 January 2021

Limited capacity for tolerization of CD4+ T cells specific for a pancreatic beta cell neo-antigen.

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7 January 2021

The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen

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7 January 2021

Expression of two alpha chains on the surface of T cells in T cell receptor transgenic mice

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7 January 2021

Expression of two T cell receptor α chains on the surface of normal murine T cells

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T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus

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Following a diabetogenic T cell from genesis through pathogenesis

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Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor

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7 January 2021

Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

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7 January 2021

Organ-specific disease provoked by systemic autoimmunity

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7 January 2021

Conditions that induce tolerance in mature CD4+ T cells

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7 January 2021

How can cryptic epitopes trigger autoimmunity?

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Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells

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7 January 2021

The joining of germ-line V alpha to J alpha genes replaces the preexisting V alpha-J alpha complexes in a T cell receptor alpha, beta positive T cell line.

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7 January 2021

Expression of two T cell receptor alpha chains: dual receptor T cells

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7 January 2021

Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in κ transgenic mice

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7 January 2021

Changes in function of antigen-specific lymphocytes correlating with progression towards diabetes in a transgenic model.

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7 January 2021

A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity

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7 January 2021

Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance

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7 January 2021

Transgenic mice with mu and kappa genes encoding antiphosphorylcholine antibodies

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7 January 2021

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7 January 2021

In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes.

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Anti-suppressor effect of cyclophosphamide on the development of spontaneous diabetes in NOD mice

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7 January 2021

Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.

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7 January 2021

Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function

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7 January 2021

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Identifiers

DOI

1 reference

7 February 2018

release_crntczay2rbb3bntf6il6x66ne

Fatcat ID

0 references

PubMed ID

9620677

1 reference

7 February 2018