A widened substrate selectivity filter of eukaryotic formate-nitrite transporters enables high-level lactate conductance (Q47995314)

7 February 2018

title

A widened substrate selectivity filter of eukaryotic formate-nitrite transporters enables high-level lactate conductance (English)

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7 February 2018

author name string

Marie Wiechert

1

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7 February 2018

Holger Erler

2

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7 February 2018

André Golldack

3

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7 February 2018

Eric Beitz

4

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7 February 2018

language of work or name

English

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publication date

21 May 2017

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7 February 2018

published in

FEBS Journal

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7 February 2018

volume

284

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7 February 2018

issue

16

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7 February 2018

page(s)

2663-2673

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7 February 2018

Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel

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Ion selectivity and gating mechanisms of FNT channels

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Isolation and characterization of hypophosphite--resistant mutants of Escherichia coli: identification of the FocA protein, encoded by the pfl operon, as a putative formate transporter

21 January 2018

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Differential turnover of the multiple processed transcripts of the Escherichia coli focA-pflB operon.

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The formate channel FocA exports the products of mixed-acid fermentation

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A single channel for nitrate uptake, nitrite export and nitrite uptake by Escherichia coli NarU and a role for NirC in nitrite export and uptake

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The roles of the polytopic membrane proteins NarK, NarU and NirC in Escherichia coli K-12: two nitrate and three nitrite transporters

21 January 2018

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Structural and functional characterization of the nitrite channel NirC from Salmonella typhimurium

21 January 2018

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Identification and characterization of a bacterial hydrosulphide ion channel

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Novel role of the nitrite transporter NirC in Salmonella pathogenesis: SPI2-dependent suppression of inducible nitric oxide synthase in activated macrophages

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Identity of a Plasmodium lactate/H(+) symporter structurally unrelated to human transporters

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High-level cell-free production of the malarial lactate transporter PfFNT as a basis for crystallization trials and directional transport studies

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Substrate-analogous inhibitors exert antimalarial action by targeting the Plasmodium lactate transporter PfFNT at nanomolar scale

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Point mutations in the aromatic/arginine region in aquaporin 1 allow passage of urea, glycerol, ammonia, and protons

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Structural determinants of the hydrogen peroxide permeability of aquaporins

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The arginine-facing amino acid residue of the rat aquaporin 1 constriction determines solute selectivity according to its size and lipophilicity

21 January 2018

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Exploring the pH-dependent substrate transport mechanism of FocA using molecular dynamics simulation.

21 January 2018

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Mechanism of selectivity in aquaporins and aquaglyceroporins.

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Structural context shapes the aquaporin selectivity filter

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21 January 2018

Identifiers

DOI

10.1111/FEBS.14117

1 reference

7 February 2018

1 reference

7 February 2018