Designing organometallic compounds for catalysis and therapy (Q48007506)

7 February 2018

title

Designing organometallic compounds for catalysis and therapy (English)

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7 February 2018

author

Abraha Habtemariam

2

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7 February 2018

Ana M Pizarro

3

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7 February 2018

author name string

Anna Louisa Noffke

1

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7 February 2018

Peter J Sadler

4

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7 February 2018

language of work or name

English

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publication date

19 April 2012

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7 February 2018

published in

Chemical Communications

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7 February 2018

volume

48

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7 February 2018

issue

43

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7 February 2018

page(s)

5219-5246

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7 February 2018

Bioorganometallic chemistry--from teaching paradigms to medicinal applications

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Tuning heavy metal compounds for anti-tumor activity: is diversity the key to ruthenium's success?

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Strength of the Zn-N coordination bond in zinc porphyrins on the basis of experimental thermochemistry

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Ruthenium-based heterocyclic carbene-coordinated olefin metathesis catalysts

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Catalysis by Palladium Pincer Complexes

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Highly active and robust Cp* iridium complexes for catalytic water oxidation

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The development of L2X2Ru=CHR olefin metathesis catalysts: an organometallic success story

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Mechanism and activity of ruthenium olefin metathesis catalysts

21 January 2018

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From catalysts to bioactive organometallics: do Grubbs catalysts trigger biological effects?

21 January 2018

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Asymmetric Transfer Hydrogenation of Aromatic Ketones Catalyzed by Chiral Ruthenium(II) Complexes

21 January 2018

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Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones

21 January 2018

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Recent developments in pyridine nucleotide regeneration.

21 January 2018

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Regeneration of cofactors for use in biocatalysis

21 January 2018

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Chiral eta(6)-arene/N-tosylethylenediamine-ruthenium(II) complexes: solution behavior and catalytic activity for asymmetric hydrogenation

21 January 2018

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A multilateral mechanistic study into asymmetric transfer hydrogenation in water

21 January 2018

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Bioorganometallic chemistry. 13. Regioselective reduction of NAD(+) models, 1-benzylnicotinamde triflate and beta-nicotinamide ribose-5'-methyl phosphate, with in situ generated [CpRh(Bpy)H](+): structure-activity relationships, kinetics, and mechan

21 January 2018

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Industrial biocatalysis today and tomorrow

21 January 2018

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Photoenzymatic synthesis through sustainable NADH regeneration by SiO2-supported quantum dots.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CC30678F

Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.

21 January 2018

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Artificial Metalloenzymes Based on the Biotin−Avidin Technology: Enantioselective Catalysis and Beyond

21 January 2018

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Catalysis of regioselective reduction of NAD+ by ruthenium(II) arene complexes under biologically relevant conditions.

21 January 2018

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Organometallic ruthenium and iridium transfer-hydrogenation catalysts using coenzyme NADH as a cofactor

21 January 2018

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Efficient catalytic interconversion between NADH and NAD+ accompanied by generation and consumption of hydrogen with a water-soluble iridium complex at ambient pressure and temperature

21 January 2018

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A mechanistic dichotomy in scandium ion-promoted hydride transfer of an NADH analogue: delicate balance between one-step hydride-transfer and electron-transfer pathways

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CC30678F

Pincer-type Pyridine-Based N-Heterocyclic Carbene Amine Ru(II) Complexes as Efficient Catalysts for Hydrogen Transfer Reactions

21 January 2018

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Titanocene Dichloride-The First Metallocene with Cancerostatic Activity

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CC30678F

Tumor inhibition by metallocenes: antitumor activity of titanocene dihalides (C5H5)2TiX2 (X=F, Cl, Br, I, NCS) and their application in buffered solutions as a method for suppressing drug-induced side effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Titanium complexes in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Phase II trial of titanocene dichloride in advanced renal-cell carcinoma

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CC30678F

Titanium(IV) targets phosphoesters on nucleotides: implications for the mechanism of action of the anticancer drug titanocene dichloride

21 January 2018

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Binding and hydrolysis studies of antitumoural titanocene dichloride and Titanocene Y with phosphate diesters

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CC30678F

Ti(IV) uptake and release by human serum transferrin and recognition of Ti(IV)-transferrin by cancer cells: understanding the mechanism of action of the anticancer drug titanocene dichloride.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CC30678F

Functionalised cyclopentadienyl zirconium compounds as potential anticancer drugs

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CC30678F

Functionalised cyclopentadienyl titanium compounds as potential anticancer drugs

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CC30678F

Bioorganometallic fulvene-derived titanocene anti-cancer drugs

21 January 2018

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Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study

21 January 2018

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Development of bimetallic titanocene-ruthenium-arene complexes as anticancer agents: relationships between structural and biological properties.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CC30678F

Antimalarial compounds: from bench to bedside

21 January 2018

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Synthesis and antimalarial activities of rhenium bioorganometallics based on the 4-aminoquinoline structure

21 January 2018

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Facile route to ferrocifen, 1-[4-(2-dimethylaminoethoxy)]-1-(phenyl-2-ferrocenyl-but-1-ene), first organometallic analogue of tamoxifen, by the McMurry reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Synthetic and mechanistic pathways of cis and trans-hydroxytamoxifen drug derivatives reacting with Cp*Rh complexes that involve η1-N, η2-N,O, η1-O, and η6 bonding modes, via a novel N-π rearrangement; relative binding affinities and computer dockin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Synthesis, cytotoxicity, and COMPARE analysis of ferrocene and [3]ferrocenophane tetrasubstituted olefin derivatives against human cancer cells

21 January 2018

1 reference

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Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol

21 January 2018

1 reference

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Ferrocenyl quinone methides as strong antiproliferative agents: formation by metabolic and chemical oxidation of ferrocenyl phenols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Role of aromatic substituents on the antiproliferative effects of diphenyl ferrocenyl butene compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

A [3]ferrocenophane polyphenol showing a remarkable antiproliferative activity on breast and prostate cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Inert ruthenium half-sandwich complexes with anticancer activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Toward the development of a potent and selective organoruthenium mammalian sterile 20 kinase inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Targeting proteins with metal complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

From conventional to unusual enzyme inhibitor scaffolds: the quest for target specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Cellular copper transport and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Arene ruthenium complexes as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Development of organometallic ruthenium-arene anticancer drugs that resist hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Metal-based antitumour drugs in the post genomic era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Anti-tumour activity in non-small cell lung cancer models and toxicity profiles for novel ruthenium(II) based organo-metallic compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Reactivity of an antimetastatic organometallic ruthenium compound with metallothionein-2: relevance to the mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Studies on the reactivity of organometallic Ru-, Rh- and Os-pta complexes with DNA model compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Rationalization of the inhibition activity of structurally related organometallic compounds against the drug target cathepsin B by DFT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Organometallic cis-Dichlorido Ruthenium(II) Ammine Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Controlling the reactivity of ruthenium(II) arene complexes by tether ring-opening

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Controlling ligand substitution reactions of organometallic complexes: tuning cancer cell cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Use of chelating ligands to tune the reactive site of half-sandwich ruthenium(II)-arene anticancer complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Kinetics of aquation and anation of ruthenium(II) arene anticancer complexes, acidity and X-ray structures of aqua adducts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium(II) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Photocontrolled nucleobase binding to an organometallic Ru(II) arene complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Structure-activity relationships for cytotoxic ruthenium(II) arene complexes containing N,N-, N,O-, and O,O-chelating ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Chloro half-sandwich osmium(II) complexes: influence of chelated N,N-ligands on hydrolysis, guanine binding, and cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Tuning the hydrolytic aqueous chemistry of osmium arene complexes with N,O-chelating ligands to achieve cancer cell cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Competition between glutathione and guanine for a ruthenium(II) arene anticancer complex: detection of a sulfenato intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Oxidation induced by the antioxidant glutathione (GSH).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Influence of oxygenation on the reactivity of ruthenium-thiolato bonds in arene anticancer complexes: insights from XAS and DFT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Arene control over thiolate to sulfinate oxidation in albumin by organometallic ruthenium anticancer complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Efficient oxidation of cysteine and glutathione catalyzed by a dinuclear areneruthenium trithiolato anticancer complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Phenylazo-pyridine and phenylazo-pyrazole chlorido ruthenium(II) arene complexes: arene loss, aquation, and cancer cell cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Catalytic organometallic anticancer complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Organometallic osmium arene complexes with potent cancer cell cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Structure-activity relationships for organometallic osmium arene phenylazopyridine complexes with potent anticancer activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Ruthenium(II) arene anticancer complexes with redox-active diamine ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

The "complex-in-a-complex" cations [(acac)2M subset Ru6(p-iPrC6H4Me)6(tpt)2(dhbq)3]6+: A trojan horse for cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Evidence for drug release from a metalla-cage delivery vector following cellular internalisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Encapsulation of pyrene-functionalized poly(benzyl ether) dendrons into a water-soluble organometallic cage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Double targeting of tumours with pyrenyl-modified dendrimers encapsulated in an arene-ruthenium metallaprism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Anticancer activity of osmium metalla-rectangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Anticancer activity of tetracationic arene ruthenium metalla-cycles

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Anticancer activity of opened arene ruthenium metalla-assemblies

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Ruthenium- and Osmium-Arene Complexes of 2-Substituted Indolo[3,2-c]quinolines: Synthesis, Structure, Spectroscopic Properties, and Antiproliferative Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

First ruthenium organometallic complex of antibacterial agent ofloxacin. Crystal structure and interactions with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Physicochemical Studies and Anticancer Potency of Ruthenium η-p-Cymene Complexes Containing Antibacterial Quinolones

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Ruthenium(II)-arene complexes with functionalized pyridines: synthesis, characterization and cytotoxic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Maltol-derived ruthenium-cymene complexes with tumor inhibiting properties: the impact of ligand-metal bond stability on anticancer activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

From hydrolytically labile to hydrolytically stable Ru(II)-arene anticancer complexes with carbohydrate-derived co-ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Is the reactivity of M(II)-arene complexes of 3-hydroxy-2(1H)-pyridones to biomolecules the anticancer activity determining parameter?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Amide linkage isomerism as an activity switch for organometallic osmium and ruthenium anticancer complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Cytotoxicity, hydrophobicity, uptake, and distribution of osmium(II) anticancer complexes in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Binding of organometallic ruthenium(II) anticancer compounds to nucleobases: a computational study

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Metal complexes as DNA intercalators

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Induced-fit recognition of DNA by organometallic complexes with dynamic stereogenic centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Isomer separation and gas-phase configurations of organoruthenium anticancer complexes: ion mobility mass spectrometry and modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Cytotoxicity, cellular uptake, and DNA interactions of new monodentate ruthenium(II) complexes containing terphenyl arenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Differences in the cellular response and signaling pathways between cisplatin and monodentate organometallic Ru(II) antitumor complexes containing a terphenyl ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Use of ion mobility mass spectrometry and a collision cross-section algorithm to study an organometallic ruthenium anticancer complex and its adducts with a DNA oligonucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Conformation of DNA modified by monofunctional Ru(II) arene complexes: recognition by DNA binding proteins and repair. Relationship to cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Energetics, conformation, and recognition of DNA duplexes modified by monodentate Ru(II) complexes containing terphenyl arenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Organometallic half-sandwich iridium anticancer complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

A novel ruthenium(II) arene based intercalator with potent anticancer activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

Asymmetric Transfer Hydrogenation in Water with Platinum Group Metal Catalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CC30678F

(p-cymene)RuLCl₂ (L = 1,3-Bis(2,4,6-trimethylphenyl)imidazol-2-ylidene and 1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene) and Related Complexes as Ring Closing Metathesis Catalysts

21 January 2018

1 reference

18 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1021/OM990357F

Identifiers

DOI

10.1039/C2CC30678F

1 reference

7 February 2018

1 reference

7 February 2018