Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice. (Q48011121)

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1 November 2019

title

Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice (English)

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amyotrophic lateral sclerosis

1 November 2019

main subject

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author

Manabu Wada

5

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1 November 2019

author name string

Shinsuke Tobisawa

1

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1 November 2019

Yasukazu Hozumi

2

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1 November 2019

Shigeki Arawaka

3

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1 November 2019

Shingo Koyama

4

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1 November 2019

Makiko Nagai

6

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1 November 2019

Masashi Aoki

7

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1 November 2019

Yasuto Itoyama

8

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1 November 2019

Kaoru Goto

9

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1 November 2019

Takeo Kato

10

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1 November 2019

language of work or name

English

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publication date

1 April 2003

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Biochemical and Biophysical Research Communications

1 November 2019

published in

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1 November 2019

volume

303

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1 November 2019

issue

2

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1 November 2019

page(s)

496-503

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Erratum: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 November 2019

cites work

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Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

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Mutations in all five exons ofSOD-1 may cause ALS

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Mild ALS in Japan associated with novel SOD mutation

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A novel SOD mutant and ALS

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Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis

7 January 2021

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Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

7 January 2021

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

7 January 2021

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An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

7 January 2021

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Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

7 January 2021

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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

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Molecular genetic basis of familial ALS.

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Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

7 January 2021

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Toxic mutants in Charcot's sclerosis

7 January 2021

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Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

7 January 2021

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ALS, SOD and peroxynitrite

7 January 2021

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Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

7 January 2021

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Medicine: danger--misfolding proteins.

7 January 2021

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Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

7 January 2021

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

7 January 2021

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Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

7 January 2021

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pEF-BOS, a powerful mammalian expression vector

7 January 2021

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A 104-kDa diacylglycerol kinase containing ankyrin-like repeats localizes in the cell nucleus

7 January 2021

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Galectin-1 Is a Component of Neurofilamentous Lesions in Sporadic and Familial Amyotrophic Lateral Sclerosis

7 January 2021

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Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS

7 January 2021

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Formation of granular cytoplasmic aggregates in COS7 cells expressing mutant Cu/Zn superoxide dismutase associated with familial amyotrophic lateral sclerosis.

7 January 2021

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Tripartite management of unfolded proteins in the endoplasmic reticulum

7 January 2021

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Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

7 January 2021

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7 January 2021

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Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria

7 January 2021

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Decreased levels of proteasome activity and proteasome expression in aging spinal cord

7 January 2021

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The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome

7 January 2021

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An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

7 January 2021

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7 January 2021

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12659845%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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