A mouse model of a human multiple GIST family with KIT-Asp820Tyr mutation generated by a knock-in strategy. (Q48013301)

7 February 2018

title

A mouse model of a human multiple GIST family with KIT-Asp820Tyr mutation generated by a knock-in strategy. (English)

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7 February 2018

author name string

Nakai N

1

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7 February 2018

Ishikawa T

2

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7 February 2018

Nishitani A

3

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7 February 2018

Liu NN

4

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7 February 2018

Shincho M

5

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7 February 2018

Hao H

6

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7 February 2018

Isozaki K

7

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7 February 2018

Kanda T

8

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7 February 2018

Nishida T

9

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7 February 2018

Fujimoto J

10

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7 February 2018

Hirota S

11

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7 February 2018

publication date

1 February 2008

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7 February 2018

published in

Journal of Pathology

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7 February 2018

volume

214

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7 February 2018

issue

3

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7 February 2018

page(s)

302-311

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7 February 2018

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

cites work

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The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

21 January 2018

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The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

21 January 2018

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Interstitial cells of Cajal generate a rhythmic pacemaker current

21 January 2018

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W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity

21 January 2018

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Disturbed intestinal movement, bile reflux to the stomach, and deficiency of c-kit-expressing cells in Ws/Ws mutant rats

21 January 2018

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Identification of a ligand for the c-kit proto-oncogene

21 January 2018

1 reference

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

21 January 2018

1 reference

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

21 January 2018

1 reference

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

21 January 2018

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Activating c-kit gene mutations in human germ cell tumors

21 January 2018

1 reference

KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors

21 January 2018

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Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases

21 January 2018

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Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours

21 January 2018

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c-kit gene mutation at exon 17 or 13 is very rare in sporadic gastrointestinal stromal tumors

21 January 2018

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Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

21 January 2018

1 reference

Familial gastrointestinal stromal tumours with germline mutation of the KIT gene

21 January 2018

1 reference

Germline-activating mutation in the kinase domain of KIT gene in familial gastrointestinal stromal tumors

21 January 2018

1 reference

Germline mutation in the juxtamembrane domain of the kit gene in a family with gastrointestinal stromal tumors and urticaria pigmentosa

21 January 2018

1 reference

Familial gastrointestinal stromal tumors associated with dysphagia and novel type germline mutation of KIT gene

21 January 2018

1 reference

Pleomorphic characteristics of a germ-line KIT mutation in a large kindred with gastrointestinal stromal tumors, hyperpigmentation, and dysphagia

21 January 2018

1 reference

Multiple gastrointestinal stromal tumors with a germline c-kit mutation.

21 January 2018

1 reference

Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis

21 January 2018

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Gastrointestinal stromal tumors: insights from a new familial GIST kindred with unusual genetic and pathologic features

21 January 2018

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Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase

21 January 2018

1 reference

A knock-in mouse model of gastrointestinal stromal tumor harboring kit K641E.

21 January 2018

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Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses

21 January 2018

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Imatinib inhibits various types of activating mutant kit found in gastrointestinal stromal tumors

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.2296

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7 February 2018

PubMed ID

18098338

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7 February 2018