SEC-TID: A Label-Free Method for Small-Molecule Target Identification (Q48019814)

7 February 2018

title

SEC-TID: A Label-Free Method for Small-Molecule Target Identification (English)

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7 February 2018

author name string

Michael Salcius

1

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Andras J Bauer

2

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Qin Hao

3

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Shu Li

4

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Antonin Tutter

5

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Jacob Raphael

6

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Wolfgang Jahnke

7

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Jean-Michel Rondeau

8

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Emmanuelle Bourgier

9

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John Tallarico

10

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Gregory A Michaud

11

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publication date

19 February 2014

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Journal of Biomolecular Screening

published in

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volume

19

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issue

6

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page(s)

917-927

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Identifying mechanism-of-action targets for drugs and probes.

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Structure and ligand of a histone acetyltransferase bromodomain

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The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

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Dual binding mode of a novel series of DHODH inhibitors.

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The history of diclofenac

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Pharmacology of diclofenac sodium

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The macro domain is an ADP-ribose binding module

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Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid

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5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential

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Characterization and inhibition of the recently discovered carbonic anhydrase isoforms CA XIII, XIV and XV.

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Recent advances in research on the most novel carbonic anhydrases, CA XIII and XV.

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Modern diuretics and the kidney

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Mechanisms of the antitumor activity of human Vγ9Vδ2 T cells in combination with zoledronic acid in a preclinical model of neuroblastoma.

21 January 2018

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Pharmacologic activation of the innate immune system to prevent respiratory viral infections

21 January 2018

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Type 1 responses of human Vγ9Vδ2 T cells to influenza A viruses

21 January 2018

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Carbonic Anhydrase Inhibitors: Clash with Ala65 as a Means for Designing Inhibitors with Low Affinity for the Ubiquitous Isozyme II, Exemplified by the Crystal Structure of the Topiramate Sulfamide Analogue†

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21 January 2018

Identifiers

DOI

10.1177/1087057114522691

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7 February 2018

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7 February 2018