WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family. (Q48024609)

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25 January 2020

title

WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family (English)

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9

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Diana Pacheco-Alvarez

1

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María Castañeda-Bueno

3

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6

Erika Moreno

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8

Norma A Bobadilla

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Norma Elizabeth Vázquez-Herrera

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2

object named as

Norma Vázquez

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4

Paola de-Los-Heros

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author name string

César Cortes-González

5

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Patricia Meade

7

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publication date

1 March 2012

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Cellular Physiology and Biochemistry

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published in

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volume

29

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issue

1-2

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page(s)

291-302

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Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.

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cites work

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Regulation of K-Cl cotransport: from function to genes

21 January 2018

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Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody

21 January 2018

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PASK (Proline-Alanine-rich STE20-related Kinase), a Regulatory Kinase of the Na-K-Cl Cotransporter (NKCC1)

21 January 2018

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WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway

21 January 2018

1 reference

WNK3 modulates transport of Cl- in and out of cells: implications for control of cell volume and neuronal excitability.

21 January 2018

1 reference

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis

21 January 2018

1 reference

WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters

21 January 2018

1 reference

Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter

21 January 2018

1 reference

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)

21 January 2018

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Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase

21 January 2018

1 reference

SPAK and OSR1, key kinases involved in the regulation of chloride transport

21 January 2018

1 reference

Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways

21 January 2018

1 reference

Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

21 January 2018

1 reference

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

21 January 2018

1 reference

WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.

21 January 2018

1 reference

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

21 January 2018

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Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases

21 January 2018

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WNK4 kinase is a negative regulator of K+-Cl- cotransporters.

21 January 2018

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Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4.

21 January 2018

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The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion

21 January 2018

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A single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters

21 January 2018

1 reference

A novel N-terminal isoform of the neuron-specific K-Cl cotransporter KCC2.

21 January 2018

1 reference

The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway

21 January 2018

1 reference

Role of the WNK-activated SPAK kinase in regulating blood pressure

21 January 2018

1 reference

SPAK and OSR1: STE20 kinases involved in the regulation of ion homoeostasis and volume control in mammalian cells

21 January 2018

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Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

21 January 2018

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WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia

21 January 2018

1 reference

Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000337610

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