Humanization of an antibody recognizing a breast cancer specific epitope by CDR-grafting (Q48052852)

8 February 2018

title

Humanization of an antibody recognizing a breast cancer specific epitope by CDR-grafting (English)

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8 February 2018

3

Gallo RC

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8 February 2018

Fiorentini S

1

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8 February 2018

Matczak E

2

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8 February 2018

Reitz MS

4

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8 February 2018

Keydar I

5

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8 February 2018

Watkins BA

6

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8 February 2018

publication date

1 March 1997

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8 February 2018

Immunotechnology : an international journal of immunological engineering

published in

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8 February 2018

volume

3

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8 February 2018

issue

1

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8 February 2018

page(s)

45-59

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8 February 2018

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Isolation and characterization of an expressed hypervariable gene coding for a breast-cancer-associated antigen

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A transcribed gene, containing a variable number of tandem repeats, codes for a human epithelial tumor antigen. cDNA cloning, expression of the transfected gene and over-expression in breast cancer tissue

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Characterization and molecular cloning of a novel MUC1 protein, devoid of tandem repeats, expressed in human breast cancer tissue.

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DNA methylation status of the MUC1 gene coding for a breast-cancer-associated protein

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A short sequence, within the amino acid tandem repeat of a cancer-associated mucin, contains immunodominant epitopes

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The role of tumor-associated antigens in the biology and immunotherapy of breast cancer.

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Immunogenicity of synthetic peptides related to the core peptide sequence encoded by the human MUC1 mucin gene: effect of immunization on the growth of murine mammary adenocarcinoma cells transfected with the human MUC1 gene

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Establishment and characterization of a cell line of human breast carcinoma origin

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Recognition of peptidyl epitopes by polymorphic epithelial mucin (PEM)-specific monoclonal antibodies

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Reshaping human antibodies for therapy

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Reshaping human antibodies: grafting an antilysozyme activity

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Replacing the complementarity-determining regions in a human antibody with those from a mouse

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Immunoglobulin complementarity-determining region grafting by recombinant polymerase chain reaction to generate humanised monoclonal antibodies

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Polymerase chain reaction facilitates the cloning, CDRgrafting, and rapid expression of a murine monoclonal antibody directed against the CD18 component of leukocyte integrins

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'Sticky feet'-directed mutagenesis and its application to swapping antibody domains

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V-region and class specific RT-PCR amplification of human immunoglobulin heavy and light chain genes from B-cell lines.

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Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda

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Dideoxy sequencing method using denatured plasmid templates

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An efficient and reproducible procedure for the formation of spheroplasts from variously grown Escherichia coli

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Antigenic expression by cells derived from human gliomas does not correlate with morphological classification.

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The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

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Two kappa immunoglobulin genes are expressed in the myeloma S107.

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7 January 2021

Antibody framework residues affecting the conformation of the hypervariable loops

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7 January 2021

Humanization of a mouse monoclonal antibody by CDR–grafting: the importance of framework residues on loop conformation

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7 January 2021

Humanization of a mouse anti-human interleukin-6 receptor antibody comparing two methods for selecting human framework regions

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7 January 2021

Minor human antibody response to a mouse and chimeric monoclonal antibody after a single i.v. infusion in ovarian carcinoma patients: a comparison of five assays

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7 January 2021

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Identifiers

DOI

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8 February 2018

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8 February 2018