Decreased AKT1/mTOR pathway mRNA expression in short-term bipolar disorder. (Q48105706)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25726893%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Decreased AKT1/mTOR pathway mRNA expression in short-term bipolar disorder (English)

1 reference

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1 March 2020

1 reference

5

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1 March 2020

Rodrigo Machado-Vieira

1

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1 March 2020

Antonio L Teixeira

3

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1 March 2020

Suely K Marie

11

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10

Wagner F Gattaz

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1 March 2020

7

Sueli M Oba-Shinjo

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Marcio Gerhardt Soeiro-de-Souza

1 March 2020

6

object named as

Marcio G Soeiro-de-Souza

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1 March 2020

author name string

Marcus V Zanetti

2

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1 March 2020

Miyuki Uno

4

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1 March 2020

Rafael T de Sousa

8

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1 March 2020

Carlos A Zarate

9

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1 March 2020

language of work or name

English

0 references

publication date

16 February 2015

1 reference

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European Neuropsychopharmacology

1 March 2020

published in

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volume

25

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issue

4

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1 March 2020

page(s)

468-473

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Glutamate receptor antagonists as fast-acting therapeutic alternatives for the treatment of depression: ketamine and other compounds.

1 March 2020

cites work

1 reference

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Multiple levels of impaired neural plasticity and cellular resilience in bipolar disorder: developing treatments using an integrated translational approach

18 June 2018

1 reference

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GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine

18 June 2018

1 reference

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Predictable chronic mild stress in adolescence increases resilience in adulthood

18 June 2018

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Roles of PI3K/AKT/GSK3/mTOR Pathway in Cell Signaling of Mental Illnesses

18 June 2018

1 reference

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Bcl-2 rs956572 polymorphism is associated with increased anterior cingulate cortical glutamate in euthymic bipolar I disorder

18 June 2018

1 reference

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The possible role of the Akt signaling pathway in schizophrenia.

18 June 2018

1 reference

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Translating neurotrophic and cellular plasticity: from pathophysiology to improved therapeutics for bipolar disorder

18 June 2018

1 reference

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Neuroprotective effects of chronic exposure of SH-SY5Y to low lithium concentration involve glycolysis stimulation, extracellular pyruvate accumulation and resistance to oxidative stress.

18 June 2018

1 reference

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The Bcl-2 gene polymorphism rs956572AA increases inositol 1,4,5-trisphosphate receptor-mediated endoplasmic reticulum calcium release in subjects with bipolar disorder

18 June 2018

1 reference

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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5863235

Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients

18 June 2018

1 reference

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The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5863235

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5863235

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5863235

Lithium enhances long‐term potentiation independently of hippocampal neurogenesis in the rat dentate gyrus

18 June 2018

1 reference

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Mood stabilizers, glycogen synthase kinase-3beta and cell survival

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5863235

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5863235

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5863235

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

18 June 2018

1 reference

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Role of the mTOR signaling pathway in the rapid antidepressant action of ketamine.

18 June 2018

1 reference

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Differences in lymphocyte electron transport gene expression levels between subjects with bipolar disorder and normal controls in response to glucose deprivation stress

14 August 2018

1 reference

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Expression of mitochondria-related genes in lymphoblastoid cells from patients with bipolar disorder

14 August 2018

1 reference

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Genetic overlap between schizophrenia and bipolar disorder: A study with AKT1 gene variants and clinical phenotypes

14 August 2018

1 reference

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Cortical bcl-2 protein expression and apoptotic regulation in schizophrenia

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25726893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25726893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Peripheral blood lymphocytes from patients with bipolar disorder demonstrate apoptosis and differential regulation of advanced glycation end products and S100B

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25726893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.EURONEURO.2015.02.002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25726893%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25726893%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

25726893

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25726893%20AND%20SRC:MED&resulttype=core&format=json