Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices. (Q48122437)

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scientific article published in September 1999

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English	Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices.	scientific article published in September 1999

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scholarly article

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices. (English)

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

Christopher G. Parsons

2

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

author name string

Frankiewicz T

1

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

publication date

1 September 1999

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Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

number of pages

7

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based on heuristic

inferred from page(s)

Neuropharmacology

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

38

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Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

9

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Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

1253-1259

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Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

Effects of the uncompetitive NMDA receptor antagonist memantine on hippocampal long-term potentiation, short-term exploratory modulation and spatial memory in awake, freely moving rats.

1 reference

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Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine

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A synaptic model of memory: long-term potentiation in the hippocampus

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Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

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Memories of NMDA receptors and LTP.

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Effects of memantine and MK-801 on NMDA-induced currents in cultured neurones and on synaptic transmission and LTP in area CA1 of rat hippocampal slices

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Multiple structural determinants of voltage-dependent magnesium block in recombinant NMDA receptors

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Memantine displaces [3H]MK-801 at therapeutic concentrations in postmortem human frontal cortex

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Learning deficits induced by chronic intraventricular infusion of quinolinic acid--protection by MK-801 and memantine

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Noncompetitive NMDA receptor antagonists with fast open-channel blocking kinetics and strong voltage-dependency as potential therapeutic agents for Alzheimer's dementia

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Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).

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Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo

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Glutamate in CNS disorders as a target for drug development: an update

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Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

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Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines

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MK-801, memantine and amantadine show neuroprotective activity in the nucleus basalis magnocellularis

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Infusion of (+) -MK-801 and memantine -- contrasting effects on radial maze learning in rats with entorhinal cortex lesion.

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Uncompetitive NMDA receptor antagonists attenuate NMDA-induced impairment of passive avoidance learning and LTP.

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7 January 2021

Identifiers

10.1016/S0028-3908(99)00060-X

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

1 reference

Europe PubMed Central

8 February 2018

http://europepmc.org/abstract/MED/10471078

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