Unique cell biological profiles of retinal disease-causing missense mutations in the polarity protein Crumbs (Q48130279)

8 February 2018

http://europepmc.org/abstract/MED/28515229

title

Unique cell biological profiles of retinal disease-causing missense mutations in the polarity protein Crumbs (English)

1 reference

8 February 2018

http://europepmc.org/abstract/MED/28515229

main subject

Crumbs Dmel_CG6383

1 reference

GOA release 2020-03-11

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28515229%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Milena Pellikka

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28515229%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

17 May 2017

1 reference

8 February 2018

http://europepmc.org/abstract/MED/28515229

published in

Journal of Cell Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28515229%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

130

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28515229%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28515229%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

2147-2158

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28515229%20AND%20SRC:MED&resulttype=core&format=json

Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.

10 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

On the role of the MAGUK proteins encoded by Drosophila varicose during embryonic and postembryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Unraveling the genetic complexity of Drosophila stardust during photoreceptor morphogenesis and prevention of light-induced degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Cleaning up: ER-associated degradation to the rescue

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

CRB1 mutations in inherited retinal dystrophies

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

The Crumbs complex: from epithelial-cell polarity to retinal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Crumbs limits oxidase-dependent signaling to maintain epithelial integrity and prevent photoreceptor cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12)

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

CRB1 mutation spectrum in inherited retinal dystrophies

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Leber congenital amaurosis: genes, proteins and disease mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

CRB1: one gene, many phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Positive feedback and mutual antagonism combine to polarize Crumbs in the Drosophila follicle cell epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

ER stress in retinal degeneration: a target for rational therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

chaoptin, prominin, eyes shut and crumbs form a genetic network controlling the apical compartment of Drosophila photoreceptor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Distinct roles of Bazooka and Stardust in the specification of Drosophila photoreceptor membrane architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Multiple domains in the Crumbs Homolog 2a (Crb2a) protein are required for regulating rod photoreceptor size

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Drosophila crumbs is required to inhibit light-induced photoreceptor degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Yurt, Coracle, Neurexin IV and the Na(+),K(+)-ATPase form a novel group of epithelial polarity proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Light-dependent translocation of visual arrestin regulated by the NINAC myosin III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

SMART: recent updates, new developments and status in 2015.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Myosin V, Rab11, and dRip11 direct apical secretion and cellular morphogenesis in developing Drosophila photoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

AP-2-complex-mediated endocytosis of Drosophila Crumbs regulates polarity by antagonizing Stardust.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Integrins and the development of three-dimensional structure in the Drosophila compound eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Increased levels of the cytoplasmic domain of Crumbs repolarise developing Drosophila photoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Drosophila Crumbs prevents ectopic Notch activation in developing wings by inhibiting ligand-independent endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Ebi modulates wing growth by ubiquitin-dependent downregulation of Crumbs in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

oko meduzy and related crumbs genes are determinants of apical cell features in the vertebrate embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Crumbs regulates rhodopsin transport by interacting with and stabilizing myosin V.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

DPATJ plays a role in retinal morphogenesis and protects against light-dependent degeneration of photoreceptor cells in the Drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

A role for the extracellular domain of Crumbs in morphogenesis of Drosophila photoreceptor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Widespread macromolecular interaction perturbations in human genetic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Arrestin1 mediates light-dependent rhodopsin endocytosis and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

The Human Gene Mutation Database: building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

The apical polarity protein network in Drosophila epithelial cells: regulation of polarity, junctions, morphogenesis, cell growth, and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Adherens junctions in Drosophila retinal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Sticking together the Crumbs - an unexpected function for an old friend

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Phototransduction and retinal degeneration in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

CRUMBS is involved in the control of apical protein targeting during Drosophila epithelial development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

Rhodopsin homeostasis and retinal degeneration: lessons from the fly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1242%2FJCS.197178

21 January 2018

Identifiers

DOI

10.1242/JCS.197178

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28515229%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference