Neuropathological study on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine of the crab-eating monkey. (Q48139739)

9 February 2018

title

Neuropathological study on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine of the crab-eating monkey. (English)

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9 February 2018

author name string

J Tanaka

1

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9 February 2018

H Nakamura

2

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9 February 2018

S Honda

3

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9 February 2018

K Takada

4

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9 February 2018

S Kato

5

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9 February 2018

publication date

1 January 1988

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9 February 2018

published in

Acta Neuropathologica

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9 February 2018

volume

75

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issue

4

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9 February 2018

page(s)

370-376

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9 February 2018

https://scigraph.springernature.com/pub.10.1007/bf00687790

exact match

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cites work

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Pigments in the red nucleus and substantia nigra in man and in representative old and new world monkeys

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Sites of the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the macaque monkey include the ventral tegmental area and the locus coeruleus.

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Chronic parkinsonism secondary to intravenous injection of meperidine analogues

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Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.

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Pigment, abnormal mitochondria and laminar bodies in human sympathetic neurons. An electron microscopical study

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Primate model of parkinsonism: selective lesion of nigrostriatal neurons by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine produces an extrapyramidal syndrome in rhesus monkeys.

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The effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on presynaptic dopamine uptake sites in the mouse striatum.

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Normal MPTP binding in parkinsonian substantial nigra: evidence for extraneuronal toxin conversion in human brain.

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Locus ceruleus lesions and eosinophilic inclusions in MPTP-treated monkeys.

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12 December 2020

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

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Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

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Light- and electron-microscopic studies of intracytoplasmic acidophilic granules in the human locus ceruleus and substantia nigra

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1-Methyl-4-phenylpyridinium ion (MPP+): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra

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Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

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Long-term effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine content in young and mature mice

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Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

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A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset.

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Identifiers

DOI

10.1007/BF00687790

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9 February 2018

PubMed ID

3259063

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9 February 2018