Cell cycle regulator E2F4 is essential for the development of the ventral telencephalon. (Q48151583)

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31 December 2019

title

Cell cycle regulator E2F4 is essential for the development of the ventral telencephalon (English)

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31 December 2019

4

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31 December 2019

David S Park

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31 December 2019

author name string

Vladimir A Ruzhynsky

1

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31 December 2019

Kelly A McClellan

2

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31 December 2019

Jacqueline L Vanderluit

3

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31 December 2019

Marosh Furimsky

5

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31 December 2019

Douglas J Epstein

7

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31 December 2019

Valerie A Wallace

8

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31 December 2019

Ruth S Slack

9

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language of work or name

English

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publication date

1 May 2007

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31 December 2019

published in

Journal of Neuroscience

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31 December 2019

volume

27

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31 December 2019

issue

22

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31 December 2019

page(s)

5926-5935

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Neural precursor cells differentiating in the absence of Rb exhibit delayed terminal mitosis and deregulated E2F 1 and 3 activity.

31 December 2019

cites work

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A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve

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A highly conserved enhancer in the Dlx5/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forebrain.

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The Rb-CDK4/6 signaling pathway is critical in neural precursor cell cycle regulation

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E2F4 is essential for normal erythrocyte maturation and neonatal viability

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Loss of E2F4 activity leads to abnormal development of multiple cellular lineages

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12 December 2020

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

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12 December 2020

Induction and dorsoventral patterning of the telencephalon

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Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

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Mammalian neural tube grafting experiments: an in vitro system for mouse experimental embryology

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Sibling rivalry in the E2F family

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12 December 2020

Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development

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12 December 2020

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

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Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling

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12 December 2020

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

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Parsing the prosencephalon

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Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

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12 December 2020

Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system

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12 December 2020

Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence

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12 December 2020

Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning

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12 December 2020

Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches.

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12 December 2020

The nucleocytoplasmic shuttling of E2F4 is involved in the regulation of human intestinal epithelial cell proliferation and differentiation

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12 December 2020

p107 regulates neural precursor cells in the mammalian brain

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12 December 2020

Temporal requirement for hedgehog signaling in ventral telencephalic patterning.

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12 December 2020

p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death

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12 December 2020

The E2F family: specific functions and overlapping interests

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12 December 2020

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

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12 December 2020

Morphogens in motion: growth control of the neural tube

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12 December 2020

A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration.

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12 December 2020

A functional screen for sonic hedgehog regulatory elements across a 1 Mb interval identifies long-range ventral forebrain enhancers.

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12 December 2020

Isolation and characterization of a novel cDNA clone encoding a homeodomain that is developmentally regulated in the ventral forebrain

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12 December 2020

E2f4 regulates fetal erythropoiesis through the promotion of cellular proliferation

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12 December 2020

Novel functions for cell cycle genes in nervous system development

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12 December 2020

Pax-6, a murine paired box gene, is expressed in the developing CNS

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12 December 2020

Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development

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12 December 2020

Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions

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12 December 2020

Immunohistochemistry of a spontaneous murine ovarian teratoma with neuroepithelial differentiation. Neuron-associated beta-tubulin as a marker for primitive neuroepithelium

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12 December 2020

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

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12 December 2020

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

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Longitudinal organization of the anterior neural plate and neural tube.

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Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell.

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12 December 2020

Development of the pattern of photoreceptors in the chick retina.

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12 December 2020

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

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12 December 2020

Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development

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12 December 2020

Gli1 is a target of Sonic hedgehog that induces ventral neural tube development

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12 December 2020

Inductive interactions direct early regionalization of the mouse forebrain

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12 December 2020

Expression patterns of the E2F family of transcription factors during mouse nervous system development

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12 December 2020

Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development

1 reference

12 December 2020

Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms.

1 reference

12 December 2020

10.1523/JNEUROSCI.1538-07.2007

Identifiers

DOI

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Fatcat ID

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24 November 2022

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PubMed publication ID

17537963

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