Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide (Q48154660)

9 February 2018

title

Brain region-specific studies of the excitatory behavioral effects of morphine-3-glucuronide (English)

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9 February 2018

author name string

Halliday AJ

1

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9 February 2018

Bartlett SE

2

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9 February 2018

Colditz P

3

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9 February 2018

Smith MT

4

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9 February 2018

language of work or name

English

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publication date

1 January 1999

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9 February 2018

published in

Life Sciences

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9 February 2018

volume

65

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9 February 2018

issue

2

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9 February 2018

page(s)

225-236

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9 February 2018

The disposition of morphine and its 3- and 6-glucuronide metabolites in humans and animals, and the importance of the metabolites to the pharmacological effects of morphine.

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Morphine-3-glucuronide--a potent antagonist of morphine analgesia

7 January 2021

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Lack of morphine-6-glucuronide antinociception after morphine treatment. Is morphine-3-glucuronide involved?

7 January 2021

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Morphine-3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat

7 January 2021

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The excitatory effects of morphine-3-glucuronide are attenuated by LY274614, a competitive NMDA receptor antagonist, and by midazolam, an agonist at the benzodiazepine site on the GABAA receptor complex.

7 January 2021

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Morphine derivatives with diminished opiate receptor potency show enhanced central excitatory activity

7 January 2021

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Opioids induce convulsions and wet dog shakes in rats: mediation by hippocampal mu, but not delta or kappa opioid receptors.

7 January 2021

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Morphine and enkephalin: analgesic and epileptic properties

7 January 2021

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Intrathecal high dose morphine produces hyperalgesia in the rat

7 January 2021

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Epileptiform effects of met-enkephalin, beta-endorphin and morphine: kindling of generalized seizures and potentiation of epileptiform effects by handling

7 January 2021

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Opioid-induced epileptogenic phenomena: anatomical, behavioral, and electroencephalographic features

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Effects of naloxone on hippocampal seizure activity

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Responsiveness of genetically epilepsy-prone rats to intracerebroventricular morphine-induced convulsions

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Opioid peptides may excite hippocampal pyramidal neurons by inhibiting adjacent inhibitory interneurons

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Concentrations of morphine, morphine-6-glucuronide and morphine-3-glucuronide in serum and cerebrospinal fluid following morphine administration to patients with morphine-resistant pain.

7 January 2021

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Evidence that physical dependence on morphine is mediated by the ventral midbrain

7 January 2021

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Intrahippocampal injections of a specific mu-receptor ligand PL017 produce generalized convulsions in rats.

7 January 2021

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Quantitation of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide in Plasma and Cerebrospinal Fluid Using Solid-Phase Extraction and High-Performance Liquid Chromatography with Electrochemical Detection

7 January 2021

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Pharmacology of morphine and morphine-3-glucuronide at opioid, excitatory amino acid, GABA and glycine binding sites

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the apparent affinity of morphine-3-glucuronide at μ1-opioid receptors results from morphine contamination: demonstration using HPLC and radioligand binding

7 January 2021

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Mu receptor binding of some commonly used opioids and their metabolites

7 January 2021

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Morphine-6-O-beta-D-glucuronide but not morphine-3-O-beta-D-glucuronide binds to mu-, delta- and kappa- specific opioid binding sites in cerebral membranes

7 January 2021

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Opioid inhibition of GABA release from presynaptic terminals of rat hippocampal interneurons

7 January 2021

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Effects of morphine-3-glucuronide and morphine on the K+-evoked release of [3H]-glutamic acid and [14C]-gamma-aminobutyric acid from rat brain synaptosomes

7 January 2021

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Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture

7 January 2021

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Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons

7 January 2021

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Endogenous opiates and nociception: a possible functional role in both pain inhibition and detection as revealed by intrathecal naloxone

7 January 2021

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Low doses of naloxone produce analgesia in the mouse brain by blocking presynaptic autoinhibition of enkephalin release

7 January 2021

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Paradoxical analgesia induced by low doses of naloxone is not potentiated by complete inhibition of enkephalin degradation

7 January 2021

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Modulatory effects of Gs-coupled excitatory opioid receptor functions on opioid analgesia, tolerance, and dependence

7 January 2021

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10.1016/S0024-3205(99)00239-8

7 January 2021

Identifiers

DOI

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9 February 2018

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9 February 2018