The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering (Q48158987)

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English	The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

endoplasmic reticulum

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1 reference

based on heuristic

inferred from title

Parkinson's disease

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based on heuristic

inferred from title

2

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Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

4

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Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

1

object named as

Denis Ottolini

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Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

Alessandro Negro

3

object named as

Alessandro Negro

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Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

publication date

14 February 2013

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Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

Human Molecular Genetics

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Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

22

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Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

11

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Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

2152-2168

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

DJ-1 expression in glioblastomas shows positive correlation with p53 expression and negative correlation with epidermal growth factor receptor amplification

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

DJ-1 has a role in antioxidative stress to prevent cell death

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

DJ-1, a novel regulator of the tumor suppressor PTEN.

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6.

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Involvement of ERK1/2 signaling pathway in DJ-1-induced neuroprotection against oxidative stress

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Oxidized DJ-1 interacts with the mitochondrial protein BCL-XL.

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Mitochondria, calcium, and endoplasmic reticulum stress in Parkinson's disease

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Mitochondrial localization of DJ-1 leads to enhanced neuroprotection

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

DJ-1 decreases Bax expression through repressing p53 transcriptional activity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

The mitochondrial p53 pathway

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

p53 has a direct apoptogenic role at the mitochondria

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Mitochondrially targeted p53 has tumor suppressor activities in vivo

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Calcium-sensitive photoproteins.

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

α-Synuclein controls mitochondrial calcium homeostasis by enhancing endoplasmic reticulum-mitochondria interactions.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca(2+) transfer to sustain cell bioenergetics.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

MAM: more than just a housekeeper

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Structural and functional features and significance of the physical linkage between ER and mitochondria.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Monoubiquitylation promotes mitochondrial p53 translocation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Fusion and fission: interlinked processes critical for mitochondrial health

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https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1alpha: regulation by SUMOylation and oxidation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

The ER-mitochondria interface: the social network of cell death

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Transfected aequorin in the measurement of cytosolic Ca2+ concentration ([Ca2+]c). A critical evaluation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Dynamics of [Ca2+] in the endoplasmic reticulum and cytoplasm of intact HeLa cells. A comparative study

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT068

21 January 2018

Identifiers

10.1093/HMG/DDT068

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/23418303

ResearchGate publication ID

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