Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures. (Q48165148)

9 February 2018

title

Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures. (English)

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9 February 2018

main subject

2-pyrrolidone

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ChEBI release 2020-05-28

2

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9 February 2018

author name string

Petroff OA

1

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9 February 2018

Collins T

3

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9 February 2018

Mattson RH

4

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Rothman DL

5

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9 February 2018

publication date

1 July 1999

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9 February 2018

published in

Epilepsia

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9 February 2018

volume

40

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9 February 2018

issue

7

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9 February 2018

page(s)

958-964

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9 February 2018

Stereoselective uptake of the GABA-transaminase inhibitors gamma-vinyl GABA and gamma-acetylenic GABA into neurons and astrocytes.

cites work

1 reference

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One to three day dose intervals during subchronic treatment of epileptic gerbils with gamma-vinyl GABA: anticonvulsant efficacy and alterations in regional brain GABA levels.

21 January 2018

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Experimental studies of the influence of vigabatrin on the GABA system

21 January 2018

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Vigabatrin enhances promoted release of GABA in neonatal rat optic nerve.

21 January 2018

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The effect of different vigabatrin treatment regimens on CSF biochemistry and seizure control in epileptic patients

21 January 2018

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Cerebrospinal fluid GABA and seizure control with vigabatrin

21 January 2018

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Clinical pharmacology of vigabatrin

21 January 2018

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Effects of single doses of vigabatrin on CSF concentrations of GABA, homocarnosine, homovanillic acid and 5-hydroxyindoleacetic acid in patients with complex partial epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB00803.X

Human brain GABA levels rise rapidly after initiation of vigabatrin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1999.TB00803.X

Human brain GABA levels rise after initiation of vigabatrin therapy but fail to rise further with increasing dose.

21 January 2018

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Localization of a novel pathway for the liberation of GABA in the human CNS.

21 January 2018

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Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo

21 January 2018

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GABA neurons in seizure disorders: a review of immunocytochemical studies

21 January 2018

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In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling

21 January 2018

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Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

21 January 2018

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Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum

21 January 2018

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In vivo activity of glutaminase in the brain of hyperammonaemic rats measured by 15N nuclear magnetic resonance

21 January 2018

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Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR.

21 January 2018

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21 January 2018

Identifiers

DOI

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9 February 2018

PubMed ID

10403220

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9 February 2018