Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. (Q48180410)

9 February 2018

title

Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice. (English)

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9 February 2018

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Rhona McGonigal

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Susan K Halstead

object named as

Susan K Halstead

4

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Edward G Rowan

object named as

Edward G Rowan

2

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Hugh John Willison

8

object named as

Hugh J Willison

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9 February 2018

author name string

Kay N Greenshields

3

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9 February 2018

Peter D Humphreys

5

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9 February 2018

Russell P Rother

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9 February 2018

Koichi Furukawa

7

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9 February 2018

language of work or name

English

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publication date

30 May 2010

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9 February 2018

published in

Brain

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9 February 2018

volume

133

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9 February 2018

issue

Pt 7

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9 February 2018

page(s)

1944-1960

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9 February 2018

Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire

cites work

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barré syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Effects of tacrine, velnacrine (HP029), suronacrine (HP128), and 3,4-diaminopyridine on skeletal neuromuscular transmission in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Apparent block of K+ currents in mouse motor nerve terminals by tetrodotoxin, mu-conotoxin and reduced external sodium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

An acute axonal form of Guillain-Barré polyneuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Prognosis in the acute motor axonal form of Guillain-Barré syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Localization of major gangliosides in the PNS: implications for immune neuropathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Overexpression of GD1a ganglioside sensitizes motor nerve terminals to anti-GD1a antibody-mediated injury in a model of acute motor axonal neuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Early nodal changes in the acute motor axonal neuropathy pattern of the Guillain-Barré syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Acute motor axonal neuropathy: An antibody-mediated attack on axolemma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Complement inhibition abrogates nerve terminal injury in Miller Fisher syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

C5 inhibitor rEV576 protects against neural injury in an in vitro mouse model of Miller Fisher syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Recovery patterns and long term prognosis for axonal Guillain-Barré syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Motor nerve terminal degeneration provides a potential mechanism for rapid recovery in acute motor axonal neuropathy after Campylobacter infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Anti-GD1a antibody is associated with axonal but not demyelinating forms of Guillain-Barré syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

21 January 2018

Guillain-Barré syndrome

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Does Campylobacter jejuni infection elicit "demyelinating" Guillain-Barre syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Acute motor axonal neuropathy: a frequent cause of acute flaccid paralysis in China.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Clinical and electrophysiological aspects of acute paralytic disease of children and young adults in northern China

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Calpain inhibitors protect against axonal degeneration in a model of anti-ganglioside antibody-mediated motor nerve terminal injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Anti-ganglioside antibodies can bind peripheral nerve nodes of Ranvier and activate the complement cascade without inducing acute conduction block in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Complement inhibitor prevents disruption of sodium channel clusters in a rabbit model of Guillain-Barré syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Pathophysiological actions of neuropathy-related anti-ganglioside antibodies at the neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

The local differentiation of myelinated axons at nodes of Ranvier

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

The complement system in the peripheral nerve: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Molecular specializations at nodes and paranodes in peripheral nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

The distribution of ganglioside-like moieties in peripheral nerves.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

In vitro analysis of glial cell function in ganglioside-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Gangliosides contribute to stability of paranodal junctions and ion channel clusters in myelinated nerve fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Acute motor axonal neuropathy rabbit model: immune attack on nerve root axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Anti-GM1 antibodies cause complement-mediated disruption of sodium channel clusters in peripheral motor nerve fibers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

Heteromultimeric K+ channels in terminal and juxtaparanodal regions of neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

The role of complement and complement regulators in mediating motor nerve terminal injury in murine models of Guillain-Barré syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ119

21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWQ119

1 reference

9 February 2018

PubMed ID

20513658

1 reference

9 February 2018