Accentuated apoptosis in normally developing p53 knockout mouse embryos following genotoxic stress. (Q48191611)

9 February 2018

title

Accentuated apoptosis in normally developing p53 knockout mouse embryos following genotoxic stress. (English)

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9 February 2018

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8

Rotter V

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9 February 2018

author name string

Frenkel J

1

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9 February 2018

Sherman D

2

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9 February 2018

Fein A

3

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9 February 2018

Schwartz D

4

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9 February 2018

Almog N

5

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9 February 2018

Kapon A

6

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Goldfinger N

7

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9 February 2018

language of work or name

English

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publication date

1 May 1999

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9 February 2018

published in

Oncogene

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9 February 2018

volume

18

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9 February 2018

issue

18

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9 February 2018

page(s)

2901-2907

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9 February 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202518

exact match

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cites work

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Cell proliferation, DNA repair, and p53 function are not required for programmed death of prostatic glandular cells induced by androgen ablation

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Quantitation and characterization of a species-specific and embryo stage-dependent 55-kilodalton phosphoprotein also present in cells transformed by simian virus 40

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

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Programmed cell death in animal development

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Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

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p73 is a simian [correction of human] p53-related protein that can induce apoptosis

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

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Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53.

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Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

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p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of EGF and insulin.

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An embryo protein induced by SV40 virus transformation of mouse cells

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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

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An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

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A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice.

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p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors

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The genetic regulation of apoptosis

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p53-mediated cell death: relationship to cell cycle control

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

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DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

21 January 2018

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Involvement of p53 in cell differentiation and development

21 January 2018

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7 January 2021

Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys

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7 January 2021

The phosphoprotein p53 is down-regulated post-transcriptionally during embryogenesis in vertebrates

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7 January 2021

Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2/M-associated cell death after gamma-irradiation

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7 January 2021

p53-dependent apoptosis suppresses radiation-induced teratogenesis

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Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development

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7 January 2021

A subset of p53-deficient embryos exhibit exencephaly

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7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202518

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9 February 2018

Dimensions Publication ID

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9 February 2018