Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling alpha 7-type neuronal nicotinic acetylcholine receptors (Q48203305)

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scientific article published in May 1999

Language	Label	Description	Also known as
English	Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling alpha 7-type neuronal nicotinic acetylcholine receptors	scientific article published in May 1999

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling alpha 7-type neuronal nicotinic acetylcholine receptors (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

Ian S Blagbrough

3

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

author name string

Davies AR

1

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

Hardick DJ

2

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

Potter BV

4

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

Wolstenholme AJ

5

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

Wonnacott S

6

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

publication date

1 May 1999

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

number of pages

12

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based on heuristic

inferred from page(s)

Neuropharmacology

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

38

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

5

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

679-690

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons.

1 reference

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Homomeric and native alpha 7 acetylcholine receptors exhibit remarkably similar but non-identical pharmacological properties, suggesting that the native receptor is a heteromeric protein complex.

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Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family

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A rapid filtration assay for soluble receptors using polyethylenimine-treated filters

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The alpha-bungarotoxin-binding nicotinic acetylcholine receptor from rat brain contains only the alpha7 subunit.

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin.

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The fall and rise of neuronal alpha-bungarotoxin binding proteins

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Rapid and efficient isolation of the nicotinic receptor antagonist methyllycaconitine from delphinium: Assignment of the methylsuccinimide absolute stereochemistry as S

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An HPLC assay for the norditerpenoid alkaloid methyllycaconitine, a potent nicotinic acetylcholine receptor antagonist.

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Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions

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A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

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Methyl lycaconitine: A novel nicotinic antagonist.

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The functional diversity of the neuronal nicotinic acetylcholine receptors is increased by a novel subunit: beta 4.

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Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

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Formation of oligomers containing the beta3 and beta4 subunits of the rat nicotinic receptor

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Behavioural and ligand-binding studies in rats with 1-acetyl-4-methylpiperazine, a novel nicotinic agonist.

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Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain

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A functional alpha-bungarotoxin receptor is present in chick cerebellum: purification and characterization

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Pharmacology and biophysical properties of alpha 7 and alpha 7-alpha 8 alpha-bungarotoxin receptor subtypes immunopurified from the chick optic lobe.

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Glutamate and GABA release are enhanced by different subtypes of presynaptic nicotinic receptors in the lateral geniculate nucleus.

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Conversion of the sodium channel activator aconitine into a potent alpha 7-selective nicotinic ligand.

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Nudicauline and elatine as potent norditerpenoid ligands at rat neuronal alpha-bungarotoxin binding sites: importance of the 2-(methylsuccinimido)benzoyl moiety for neuronal nicotinic acetylcholine receptor binding.

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Three subtypes of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors are expressed in chick retina.

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7 January 2021

Neuronal Nicotinic Receptor Subtypes

1 reference

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Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems

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The principal toxin ofDelphinium brownii Rydb., and its mode of action

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Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine.

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Functional contributions of alpha5 subunit to neuronal acetylcholine receptor channels.

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Nicotinic receptors in the development and modulation of CNS synapses.

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Distribution of alpha-bungarotoxin binding sites in the central nervous system and peripheral organs of the rat

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Brain alpha-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily

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Neuronal nicotinic acetylcholine receptor beta-subunit is coded for by the cDNA clone alpha 4.

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alpha-Bungarotoxin binds to low-affinity nicotine binding sites in rat brain.

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Interrelationship of carbohydrate and the α-toxin binding site on the acetylcholine receptor from

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Functional contribution of the alpha5 subunit to neuronal nicotinic channels expressed by chick sympathetic ganglion neurones.

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Nicotinic acetylcholine receptors in separate brain regions exhibit different affinities for methyllycaconitine.

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7 January 2021

Identifiers

10.1016/S0028-3908(98)00221-4

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 February 2018

http://europepmc.org/abstract/MED/10340305

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