Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma. (Q48209763)

9 February 2018

title

Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma. (English)

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9 February 2018

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Friedrich Weber

1

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Anthony Asher

2

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Richard Bucholz

3

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Mitchel Berger

4

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Michael Prados

5

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Susan Chang

6

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Jeffrey Bruce

7

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Walter Hall

8

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Nikolai G Rainov

9

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Manfred Westphal

10

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Ronald E Warnick

11

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Robert W Rand

12

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Frank Floeth

13

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Frank Rommel

14

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Henry Pan

15

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Vijay N Hingorani

16

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Raj K Puri

17

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publication date

1 August 2003

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Journal of Neuro-Oncology

published in

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volume

64

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page(s)

125-137

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issue

1-2

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https://scigraph.springernature.com/pub.10.1007/bf02700027

exact match

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cites work

Immunoconjugates made of an anti-EGF receptor monoclonal antibody and type 1 ribosome-inactivating proteins from Saponaria ocymoides or Vaccaria pyramidata

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Crossref

https://api.crossref.org/works/10.1007%2FBF02700027

Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with high-grade glioma.

21 January 2018

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12 December 2020

Is reoperation for recurrence of glioblastoma justified?

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Efficacy of direct intratumoral therapy with targeted protein toxins for solid human gliomas in nude mice.

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12 December 2020

Tumor antigens in astrocytic gliomas

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Convection-enhanced delivery of macromolecules in the brain

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12 December 2020

Targeting the EGF receptor in breast cancer treatment

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12 December 2020

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12 December 2020

An improved circularly permuted interleukin 4-toxin is highly cytotoxic to human renal cell carcinoma cells. Introduction of gamma c chain in RCC cells does not improve sensitivity

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12 December 2020

Interleukin-13 receptor as a unique target for anti-glioblastoma therapy

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12 December 2020

Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the toxic effects of IL4-Pseudomonas exotoxin chimeric protein

1 reference

12 December 2020

Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors.

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12 December 2020

Increased antitumor activity of a circularly permuted interleukin 4-toxin in mice with interleukin 4 receptor-bearing human carcinoma.

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12 December 2020

Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas.

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12 December 2020

Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion

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12 December 2020

Preclinical development of a recombinant toxin containing circularly permuted interleukin 4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma.

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12 December 2020

Descriptive epidemiology of primary brain and CNS tumors: results from the Central Brain Tumor Registry of the United States, 1990-1994

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12 December 2020

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12 December 2020

A circularly permuted recombinant interleukin 4 toxin with increased activity

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12 December 2020

Glioblastoma cell-specific expression of fibroblast growth factor receptor-1beta requires an intronic repressor of RNA splicing

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12 December 2020

In vivo expression of the interleukin 4 receptor alpha by astrocytes in epilepsy cerebral cortex.

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12 December 2020

IL-13R(alpha)2, a decoy receptor for IL-13 acts as an inhibitor of IL-4-dependent signal transduction in glioblastoma cells.

1 reference

12 December 2020

Complete regression of established human glioblastoma tumor xenograft by interleukin-4 toxin therapy

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12 December 2020

Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group

1 reference

12 December 2020

In situ expression of interleukin-4 (IL-4) receptors in human brain tumors and cytotoxicity of a recombinant IL-4 cytotoxin in primary glioblastoma cell cultures

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02700027

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9 February 2018

release_2ryhrgms45gspeh7ny2i6yfm3a

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2ryhrgms45gspeh7ny2i6yfm3a

24 November 2022

mapped directly with Wikidata item

PubMed ID

12952293

1 reference

9 February 2018