An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins. (Q48220231)

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1 March 2020

title

An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins (English)

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13

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Xinying Jia

9

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1 March 2020

Xinying Jia

10

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1 March 2020

Attila Mandi

12

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author name string

Zhenhua Tian

1

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1 March 2020

Peng Sun

2

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1 March 2020

Yan Yan

3

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1 March 2020

Zhuhua Wu

4

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1 March 2020

Qingfei Zheng

5

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Shuaixiang Zhou

6

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Hua Zhang

7

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1 March 2020

Futao Yu

8

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Dandan Chen

11

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Wen Liu

14

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publication date

2 March 2015

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1 March 2020

published in

Nature Chemical Biology

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volume

11

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issue

4

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page(s)

259-265

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Recent advances in the field of bioactive tetronates

1 March 2020

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Quartromicin biosynthesis: two alternative polyketide chains produced by one polyketide synthase assembly line

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Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

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A tylosin ketoreductase reveals how chirality is determined in polyketides

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Polyketide double bond biosynthesis. Mechanistic analysis of the dehydratase-containing module 2 of the picromycin/methymycin polyketide synthase

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Insight into a natural Diels-Alder reaction from the structure of macrophomate synthase

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Complete reconstitution of a highly reducing iterative polyketide synthase

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Mechanistic insights on riboflavin synthase inspired by selective binding of the 6,7-dimethyl-8-ribityllumazine exomethylene anion

21 January 2018

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Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A.

21 January 2018

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12 December 2020

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Identifiers

DOI

10.1038/NCHEMBIO.1769

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1 March 2020

Fatcat ID

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mapped directly with Wikidata item

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