Blood and cerebrospinal fluid pharmacokinetics of the novel anticonvulsant levetiracetam (ucb L059) in the rat. (Q48233188)

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4 December 2019

title

Blood and cerebrospinal fluid pharmacokinetics of the novel anticonvulsant levetiracetam (ucb L059) in the rat (English)

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4 December 2019

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3

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4 December 2019

author name string

H C Doheny

1

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4 December 2019

N Ratnaraj

2

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4 December 2019

J G Jefferys

4

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4 December 2019

P N Patsalos

5

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4 December 2019

publication date

1 April 1999

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4 December 2019

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4 December 2019

volume

34

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4 December 2019

issue

2-3

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4 December 2019

page(s)

161-168

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JANA: a new iterative polyexponential curve stripping program.

4 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

ucb L059, a novel anti-convulsant drug: pharmacological profile in animals

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7 January 2021

Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy

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7 January 2021

Photosensitive epilepsy: a model to study the effects of antiepileptic drugs. Evaluation of the piracetam analogue, levetiracetam

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7 January 2021

Antiepileptic drug pharmacokinetics and neuropharmacokinetics in individual rats by repetitive withdrawal of blood and cerebrospinal fluid: phenytoin

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

Profile of ucb L059, a novel anticonvulsant drug, in models of partial and generalized epilepsy in mice and rats

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

The novel antiepileptic drug levetiracetam (ucb L059) induces alterations in GABA metabolism and turnover in discrete areas of rat brain and reduces neuronal activity in substantia nigra pars reticulata.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

ucb L059, a novel anticonvulsant, reduces bicuculline-induced hyperexcitability in rat hippocampal CA3 in vivo

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7 January 2021

Inhibition by levetiracetam of a non-GABAA receptor-associated epileptiform effect of bicuculline in rat hippocampus

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7 January 2021

The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

A freely moving and behaving rat model for the chronic and simultaneous study of drug pharmacokinetics (blood) and neuropharmacokinetics (cerebrospinal fluid): hematological and biochemical characterization and kinetic evaluation using carbamazepine

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7 January 2021

A micromethod for the determination of the new antiepileptic drug levetiracetam (ucb LO59) in serum or plasma by high performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

Antiepileptic drug pharmacokinetics and neuropharmacokinetics in individual rats by repetitive withdrawal of blood and cerebrospinal fluid: milacemide

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

Efficacy and tolerability study of ucb L059 in patients with refractory epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

Neurochemical studies with the novel anticonvulsant levetiracetam in mouse brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

Concurrent monitoring of central carbamazepine and transmitter amine metabolism and motor activity in individual unrestrained rats using repetitive withdrawal of cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

Clinical pharmacokinetics of new antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

Comparison of single- and repeated-dose pharmacokinetics of diazepam.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2898%2900104-1

7 January 2021

10.1016/S0920-1211(98)00104-1

Identifiers

DOI

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release_ok4shsiktvcx3jmbfnl6aktc4y

4 December 2019

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/ok4shsiktvcx3jmbfnl6aktc4y

24 November 2022

mapped directly with Wikidata item

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