Importance of cycle timing for the function of the molecular chaperone Hsp90. (Q48265297)

10 February 2018

title

Importance of cycle timing for the function of the molecular chaperone Hsp90. (English)

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10 February 2018

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8

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Klaus Richter

object named as

Klaus Richter

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Tobias Madl

object named as

Tobias Madl

4

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author name string

Bettina K Zierer

1

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10 February 2018

Martin Rübbelke

2

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Franziska Tippel

3

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Florian H Schopf

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Daniel A Rutz

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Johannes Buchner

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publication date

10 October 2016

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Nature Structural & Molecular Biology

published in

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volume

23

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issue

11

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page(s)

1020-1028

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describes a project that uses

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6248305/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

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Hsp90: a specialized but essential protein-folding tool

21 January 2018

1 reference

Heat-shock protein 90, a chaperone for folding and regulation

21 January 2018

1 reference

Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches.

21 January 2018

1 reference

The chaperone Hsp90: changing partners for demanding clients

21 January 2018

1 reference

Hsp90: breaking the symmetry.

21 January 2018

1 reference

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

21 January 2018

1 reference

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

21 January 2018

1 reference

Mechanism of Dimer Formation of the 90‐kDa Heat‐Shock Protein

21 January 2018

1 reference

Dissection of the contribution of individual domains to the ATPase mechanism of Hsp90.

21 January 2018

1 reference

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains

21 January 2018

1 reference

Tetratricopeptide repeat cochaperones in steroid receptor complexes

21 January 2018

1 reference

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

21 January 2018

1 reference

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

21 January 2018

1 reference

Designed Hsp90 heterodimers reveal an asymmetric ATPase-driven mechanism in vivo.

21 January 2018

1 reference

Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements

21 January 2018

1 reference

Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex

21 January 2018

1 reference

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90.

21 January 2018

1 reference

The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis

21 January 2018

1 reference

Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90.

21 January 2018

1 reference

N-terminal residues regulate the catalytic efficiency of the Hsp90 ATPase cycle

21 January 2018

1 reference

Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase

21 January 2018

1 reference

A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s

21 January 2018

1 reference

Specific Arabidopsis HSP90.2 alleles recapitulate RAR1 cochaperone function in plant NB-LRR disease resistance protein regulation.

21 January 2018

1 reference

Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions

21 January 2018

1 reference

Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis

21 January 2018

1 reference

The conserved arginine 380 of Hsp90 is not a catalytic residue, but stabilizes the closed conformation required for ATP hydrolysis

21 January 2018

1 reference

Modulation of the Hsp90 chaperone cycle by a stringent client protein

21 January 2018

1 reference

Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle

21 January 2018

1 reference

Mixed Hsp90-cochaperone complexes are important for the progression of the reaction cycle

21 January 2018

1 reference

The Co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle

21 January 2018

1 reference

The hsp90 molecular chaperone modulates multiple telomerase activities

21 January 2018

1 reference

Global functional map of the p23 molecular chaperone reveals an extensive cellular network

21 January 2018

1 reference

Possible role for serine/threonine phosphorylation in the regulation of the heteroprotein complex between the hsp90 stress protein and the pp60v-src tyrosine kinase

21 January 2018

1 reference

Heat-shock protein hsp90 governs the activity of pp60v-src kinase

21 January 2018

1 reference

Nucleotide-dependent interaction of Saccharomyces cerevisiae Hsp90 with the cochaperone proteins Sti1, Cpr6, and Sba1.

21 January 2018

1 reference

The middle domain of Hsp90 acts as a discriminator between different types of client proteins

21 January 2018

1 reference

Intrinsic inhibition of the Hsp90 ATPase activity

21 January 2018

1 reference

Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo

21 January 2018

1 reference

Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity

21 January 2018

1 reference

Post-translational modifications of Hsp90 and their contributions to chaperone regulation

21 January 2018

1 reference

Coordinated ATP hydrolysis by the Hsp90 dimer

21 January 2018

1 reference

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

21 January 2018

1 reference

The CCPN data model for NMR spectroscopy: development of a software pipeline

21 January 2018

1 reference

Boundary analysis in sedimentation transport experiments: a procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile

21 January 2018

1 reference

SEDVIEW, real-time sedimentation analysis.

21 January 2018

1 reference

Chaperone function of Hsp90-associated proteins

21 January 2018

1 reference

C-terminal regions of Hsp90 are important for trapping the nucleotide during the ATPase cycle

31 March 2020

1 reference

Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1

31 March 2020

1 reference

Conformational Switching of the Molecular Chaperone Hsp90 via Regulated Phosphorylation

31 March 2020

1 reference

Purification of Hsp90 partner proteins Hop/p60, p23, and FKBP52

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.3305

1 reference

10 February 2018

release_i3hhr4eedzcqffjyi3xjr4slsy

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/i3hhr4eedzcqffjyi3xjr4slsy

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

6248305

0 references

1 reference

10 February 2018