Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling. (Q48294316)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12110168%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling (English)

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10 November 2019

1

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10 November 2019

author name string

Yuko Yasuda

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12110168%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

David Ish-Horowicz

series ordinal

3

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10 November 2019

language of work or name

English

0 references

publication date

1 July 2002

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10 November 2019

number of pages

12

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inferred from page(s)

published in

Developmental Cell

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10 November 2019

volume

3

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10 November 2019

issue

1

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10 November 2019

page(s)

63-74

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Dynamic expression of lunatic fringe suggests a link between notch signaling and an autonomous cellular oscillator driving somite segmentation.

10 November 2019

cites work

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Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm

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Dynamic expression and essential functions of Hes7 in somite segmentation

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Clock regulatory elements control cyclic expression of Lunatic fringe during somitogenesis

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A clock and wavefront model for control of the number of repeated structures during animal morphogenesis

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Molecular targets of vertebrate segmentation: two mechanisms control segmental expression of Xenopus hairy2 during somite formation.

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Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse

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FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation.

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7 January 2021

Mapping of the human Lunatic Fringe (LFNG) gene to 7p22 and Manic Fringe (MFNG) to 22q12.

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lunatic fringe is an essential mediator of somite segmentation and patterning

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Waves of mouse Lunatic fringe expression, in four-hour cycles at two-hour intervals, precede somite boundary formation.

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A series of normal stages in the development of the chick embryo

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Expression of a Delta homologue in prospective neurons in the chick

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Maintenance of somite borders in mice requires the Delta homologue DII1.

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Signalling downstream of activated mammalian Notch

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Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos

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Notch signalling and the synchronization of the somite segmentation clock

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Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system

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The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries.

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Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors

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The lunatic fringe gene is a target of the molecular clock linked to somite segmentation in avian embryos.

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Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear

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HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments

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7 January 2021

Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis.

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7 January 2021

Fringe modulates Notch-ligand interactions.

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7 January 2021

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