Guanosine protects against reperfusion injury in rat brains after ischemic stroke (Q48295676)

10 February 2018

title

Guanosine protects against reperfusion injury in rat brains after ischemic stroke (English)

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4

Patrizia Ballerini

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Patrizia Di Iorio

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Patrizia Di Iorio

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Michel P Rathbone

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Michel P Rathbone

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Patricia Giuliani

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Patricia Giuliani

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10 February 2018

Shucui Jiang

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Shucui Jiang

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author name string

Barry J Connell

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Iqbal Sayeed

3

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Monique C Saleh

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Tarek M Saleh

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Caixin Su

9

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publication date

14 November 2012

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Journal of Neuroscience Research

published in

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volume

91

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issue

2

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page(s)

262-272

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Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes

cites work

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Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP.

21 January 2018

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Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats

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Middle cerebral artery occlusion in the mouse by intraluminal suture coated with poly-L-lysine: neurological and histological validation

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Neuroprotective effects of guanosine on stroke models in vitro and in vivo

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Calcium: still center-stage in hypoxic-ischemic neuronal death

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Involvement of astrocytes in purine-mediated reparative processes in the brain

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A reversible component of cerebral injury as identified by the histochemical stain 2,3,5-triphenyltetrazolium chloride (TTC).

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Mechanisms of apoptosis induced by purine nucleosides in astrocytes.

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The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes.

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Improving outcome after stroke: overcoming the translational roadblock

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New approaches to neuroprotective drug development

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Neuroprotection with the CXCL8 inhibitor repertaxin in transient brain ischemia.

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Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke

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Neuroprotection with a calpain inhibitor in a model of focal cerebral ischemia

21 January 2018

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Guanosine promotes myelination and functional recovery in chronic spinal injury

21 January 2018

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Guanosine reduces apoptosis and inflammation associated with restoration of function in rats with acute spinal cord injury

21 January 2018

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Remyelination after chronic spinal cord injury is associated with proliferation of endogenous adult progenitor cells after systemic administration of guanosine

21 January 2018

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Metabolism and distribution of guanosine given intraperitoneally: implications for spinal cord injury

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Reperfusion and neurovascular dysfunction in stroke: from basic mechanisms to potential strategies for neuroprotection

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Reversible middle cerebral artery occlusion without craniectomy in rats

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The endoplasmic reticulum and the unfolded protein response

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Hypoxic-ischemic insult decreases glutamate uptake by hippocampal slices from neonatal rats: prevention by guanosine.

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Importance of schedule of administration in the therapeutic efficacy of guanosine: early intervention after injury enhances glutamate uptake in model of hypoxia-ischemia.

21 January 2018

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Progesterone exacerbates striatal stroke injury in progesterone-deficient female animals

21 January 2018

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Progesterone administration during reperfusion, but not preischemia alone, reduces injury in ovariectomized rats

21 January 2018

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Guanosine protects SH-SY5Y cells against beta-amyloid-induced apoptosis

21 January 2018

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MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine

21 January 2018

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Trophic effects of purines in neurons and glial cells.

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Neurotrophic effects of extracellular guanosine

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Systemic administration of guanosine promotes functional and histological improvement following an ischemic stroke in rats

21 January 2018

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Oxidative stress and neuronal death/survival signaling in cerebral ischemia

21 January 2018

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Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer

21 January 2018

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Uric acid: the oxidant-antioxidant paradox

21 January 2018

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Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion

21 January 2018

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Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo

21 January 2018

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Modulation of bone marrow-derived neutrophil signaling by H2O2: disparate effects on kinases, NF-kappaB, and cytokine expression.

21 January 2018

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Guanosine improves motor behavior, reduces apoptosis, and stimulates neurogenesis in rats with parkinsonism.

21 January 2018

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Reactive Oxygen Radicals and Pathogenesis of Neuronal Death After Cerebral Ischemia

21 January 2018

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Tissue plasminogen activator for acute ischemic stroke

21 January 2018

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Profile of glutamate uptake and cellular viability in hippocampal slices exposed to oxygen and glucose deprivation: developmental aspects and protection by guanosine

21 January 2018

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Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model

21 January 2018

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Specific [(3)H]-guanosine binding sites in rat brain membranes

21 January 2018

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Uric acid: an important antioxidant in acute ischaemic stroke

21 January 2018

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Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury

21 January 2018

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Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury.

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Identifiers

DOI

10.1002/JNR.23156

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10 February 2018

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10 February 2018