Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid. (Q48298461)

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24 December 2019

title

Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid (English)

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24 December 2019

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3

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24 December 2019

Ulf Diczfalusy

7

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24 December 2019

Ingemar Björkhem

11

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24 December 2019

Steve Meaney

1

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24 December 2019

Irina Pikuleva

8

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24 December 2019

Ingemar Björkhem

12

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2

Maura Heverin

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24 December 2019

4

Lena Ekström

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24 December 2019

author name string

Magnus Axelsson

5

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Ulla Andersson

6

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Wolfgang Sattler

10

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John Wahren

9

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24 December 2019

publication date

24 January 2007

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Journal of Lipid Research

24 December 2019

published in

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volume

48

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24 December 2019

issue

4

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24 December 2019

page(s)

944-951

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Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal

24 December 2019

cites work

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Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers.

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Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

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Metabolism of 27-, 25- and 24-hydroxycholesterol in rat glial cells and neurons.

21 January 2018

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Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen

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Uptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier model

21 January 2018

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Dehydroepiandrosterone (DHEA) metabolism in the brain: identification by liquid chromatography/mass spectrometry of the delta-4-isomer of DHEA and related steroids formed from androstenedione by mouse BV2 microglia

21 January 2018

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Characterization of the dehydroepiandrosterone (DHEA) metabolism via oxysterol 7alpha-hydroxylase and 17-ketosteroid reductase activity in the human brain

21 January 2018

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Immunohistochemical detection of the human cytochrome P4507B1: production of a monoclonal antibody after cDNA immunization

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Transport of side-chain oxidized oxysterols in the human circulation.

21 January 2018

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Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro.

21 January 2018

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Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover

21 January 2018

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Differential expression of cholesterol hydroxylases in Alzheimer's disease

21 January 2018

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Dehydroepiandrosterone 7-hydroxylase CYP7B: predominant expression in primate hippocampus and reduced expression in Alzheimer's disease.

21 January 2018

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Steroid hormones and neurosteroids in normal and pathological aging of the nervous system.

21 January 2018

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10.1194/JLR.M600529-JLR200

21 January 2018

Identifiers

DOI

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24 December 2019

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