Randomised clinical trial: effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease. (Q48316933)

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scientific article published on 14 February 2011

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English	Randomised clinical trial: effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease.	scientific article published on 14 February 2011

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22 January 2020

Randomised clinical trial: effects of monotherapy with ADX10059, a mGluR5 inhibitor, on symptoms and reflux events in patients with gastro-oesophageal reflux disease (English)

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22 January 2020

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22 January 2020

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F Zerbib

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22 January 2020

S Bruley des Varannes

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J-P Galmiche

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22 January 2020

J Tack

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22 January 2020

P Malfertheiner

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22 January 2020

C Keywood

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14 February 2011

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22 January 2020

Alimentary Pharmacology & Therapeutics

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22 January 2020

33

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911-921

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22 January 2020

The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis

1 reference

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21 January 2018

Management of heartburn not responding to proton pump inhibitors

1 reference

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Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring

1 reference

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21 January 2018

Mechanisms of lower oesophageal sphincter incompetence in patients with symptomatic gastrooesophageal reflux

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

Transient lower esophageal sphincter relaxation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

Effect of acute and chronic administration of the GABA B agonist baclofen on 24 hour pH metry and symptoms in control subjects and in patients with gastro-oesophageal reflux disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

Control of transient lower oesophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in patients with gastro-oesophageal reflux disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

Effects of lesogaberan on reflux and lower esophageal sphincter function in patients with gastroesophageal reflux disease

1 reference

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21 January 2018

Effect of lesogaberan, a novel GABA(B)-receptor agonist, on transient lower oesophageal sphincter relaxations in male subjects

1 reference

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Arbaclofen placarbil decreases postprandial reflux in patients with gastroesophageal reflux disease

1 reference

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21 January 2018

Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons.

1 reference

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Transient lower esophageal sphincter relaxations in dogs are inhibited by a metabotropic glutamate receptor 5 antagonist.

1 reference

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21 January 2018

Inhibition of transient lower esophageal sphincter relaxation and gastroesophageal reflux by metabotropic glutamate receptor ligands

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

A proof-of-concept study evaluating the effect of ADX10059, a metabotropic glutamate receptor-5 negative allosteric modulator, on acid exposure and symptoms in gastro-oesophageal reflux disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

Efficacy, tolerability and pharmacokinetics of a modified release formulation of ADX10059, a negative allosteric modulator of metabotropic glutamate receptor 5: an esophageal pH-impedance study in healthy subjects.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

Responsiveness and interpretation of a symptom severity index specific to upper gastrointestinal disorders

1 reference

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21 January 2018

Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2036.2011.04596.X

21 January 2018

Esophageal pH-impedance monitoring and symptom analysis in GERD: a study in patients off and on therapy

1 reference

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21 January 2018

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10.1111/J.1365-2036.2011.04596.X

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21320138%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

release_2jjxt4ztejbsxdvtu2ryzorrm4

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22 January 2020

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