[3H]LY341495, a highly potent, selective and novel radioligand for labeling Group II metabotropic glutamate receptors. (Q48317471)

10 February 2018

title

[3H]LY341495, a highly potent, selective and novel radioligand for labeling Group II metabotropic glutamate receptors. (English)

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10 February 2018

author name string

Ornstein PL

1

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Arnold MB

2

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Bleisch TJ

3

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Wright RA

4

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Wheeler WJ

5

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Schoepp DD

6

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language of work or name

English

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publication date

1 July 1998

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Bioorganic & Medicinal Chemistry Letters

published in

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volume

8

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issue

14

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page(s)

1919-1922

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Molecular Neurobiology of Glutamate Receptors

cites work

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The metabotropic glutamate receptors: structure and functions

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3,5-dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus

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7 January 2021

Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells

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7 January 2021

Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase.

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7 January 2021

2-Substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 1. Effects of alkyl, arylalkyl, and diarylalkyl substitution.

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7 January 2021

2-substituted (2SR)-2-amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as potent and selective antagonists of group II metabotropic glutamate receptors. 2. Effects of aromatic substitution, pharmacological characterization, and bioavailability.

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7 January 2021

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

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7 January 2021

1S,3R-ACPD-sensitive (metabotropic) [3H]glutamate receptor binding in membranes

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7 January 2021

Distribution and ontogeny of 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid-sensitive and quisqualate-insensitive [3H]glutamate binding sites in the rat brain

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7 January 2021

The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors

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7 January 2021

10.1016/S0960-894X(98)00329-1

Identifiers

DOI

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10 February 2018

PubMed ID

9873459

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10 February 2018