Heterologous expression of oxytetracycline biosynthetic gene cluster in Streptomyces venezuelae WVR2006 to improve production level and to alter fermentation process (Q48318319)

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scientific article published on 5 October 2016

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English	Heterologous expression of oxytetracycline biosynthetic gene cluster in Streptomyces venezuelae WVR2006 to improve production level and to alter fermentation process	scientific article published on 5 October 2016

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

Heterologous expression of oxytetracycline biosynthetic gene cluster in Streptomyces venezuelae WVR2006 to improve production level and to alter fermentation process (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

Streptomyces venezuelae

object named as

Streptomyces venezuelae

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based on heuristic

inferred from title

object named as

Weishan Wang

11

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author name string

Shouliang Yin

1

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

Zilong Li

2

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

Xuefeng Wang

3

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

Huizhuan Wang

4

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Europe PubMed Central

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10 February 2018

http://europepmc.org/abstract/MED/27709288

Xiaole Jia

5

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10 February 2018

http://europepmc.org/abstract/MED/27709288

Guomin Ai

6

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10 February 2018

http://europepmc.org/abstract/MED/27709288

Zishang Bai

7

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Europe PubMed Central

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10 February 2018

http://europepmc.org/abstract/MED/27709288

Mingxin Shi

8

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Europe PubMed Central

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10 February 2018

http://europepmc.org/abstract/MED/27709288

Fang Yuan

9

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10 February 2018

http://europepmc.org/abstract/MED/27709288

Tiejun Liu

10

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10 February 2018

http://europepmc.org/abstract/MED/27709288

Keqian Yang

12

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10 February 2018

http://europepmc.org/abstract/MED/27709288

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publication date

5 October 2016

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

Applied Microbiology and Biotechnology

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PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

100

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PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

24

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

10563-10572

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

https://scigraph.springernature.com/pub.10.1007/s00253-016-7873-1

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Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines

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Identification of JadG as the B ring opening oxygenase catalyzing the oxidative C-C bond cleavage reaction in jadomycin biosynthesis.

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Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis

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New tools for reconstruction and heterologous expression of natural product biosynthetic gene clusters

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The history of the tetracyclines

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Recent advances in the heterologous expression of microbial natural product biosynthetic pathways

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Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length

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21 January 2018

Oxytetracycline biosynthesis

1 reference

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21 January 2018

Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes

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21 January 2018

In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis.

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21 January 2018

Improved oxytetracycline production in Streptomyces rimosus M4018 by metabolic engineering of the G6PDH gene in the pentose phosphate pathway.

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Autoregulation of antibiotic biosynthesis by binding of the end product to an atypical response regulator

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Identification of OxyE as an ancillary oxygenase during tetracycline biosynthesis.

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Heterologous expression and manipulation of three tetracycline biosynthetic pathways.

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Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis

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An engineered strong promoter for streptomycetes

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Development of a Synthetic Oxytetracycline-Inducible Expression System for Streptomycetes Using de Novo Characterized Genetic Parts

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"Pseudo" gamma-butyrolactone receptors respond to antibiotic signals to coordinate antibiotic biosynthesis

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A repressor-response regulator gene pair controlling jadomycin B production in Streptomyces venezuelae ISP5230.

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Regulation of jadomycin B production in Streptomyces venezuelae ISP5230: involvement of a repressor gene, jadR2

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21 January 2018

Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus

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Oxytetracycline biosynthesis improvement in Streptomyces rimosus following duplication of minimal PKS genes

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Insights into naturally minimised Streptomyces albus J1074 genome.

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Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase

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Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway

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JadR*-mediated feed-forward regulation of cofactor supply in jadomycin biosynthesis.

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Enhanced flavonoid production in Streptomyces venezuelae via metabolic engineering

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12 April 2024

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10.1007/S00253-016-7873-1

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

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PubMed publication ID

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/27709288

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