alpha-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy. (Q48327676)

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2 November 2019

title

alpha-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy (English)

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2 November 2019

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6

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2 November 2019

Poul Henning Jensen

7

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2 November 2019

author name string

W P Gai

1

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2 November 2019

D L Pountney

2

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2 November 2019

J H T Power

3

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2 November 2019

Q X Li

4

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2 November 2019

J G Culvenor

5

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2 November 2019

P C Blumbergs

8

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2 November 2019

language of work or name

English

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publication date

1 May 2003

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2 November 2019

published in

Experimental Neurology

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2 November 2019

volume

181

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2 November 2019

page(s)

68-78

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2 November 2019

issue

1

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NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy

2 November 2019

cites work

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Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein

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Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

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Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

7 January 2021

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Characterisation of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain

7 January 2021

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Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.

7 January 2021

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Oligodendrocytes from neural stem cells express alpha-synuclein: increased numbers from presenilin 1 deficient mice.

7 January 2021

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Multiple system atrophy: a sporadic synucleinopathy

7 January 2021

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Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy

7 January 2021

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Conformational properties of alpha-synuclein in its free and lipid-associated states

7 January 2021

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In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies

7 January 2021

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A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

7 January 2021

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Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

7 January 2021

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Alpha-synuclein and neurodegenerative diseases

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The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

7 January 2021

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Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds alpha-synuclein filaments

7 January 2021

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Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes

7 January 2021

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Cytoplasmic argyrophilic inclusions in neurons of pontine nuclei in patients with olivopontocerebellar atrophy: immunohistochemical and ultrastructural studies.

7 January 2021

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Argyrophilic ubiquitinated cytoplasmic inclusions of Leu-7-positive glial cells in olivopontocerebellar atrophy (multiple system atrophy)

7 January 2021

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The definition of multiple system atrophy: a review of recent developments

7 January 2021

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Biochemical characterization of the core structure of alpha-synuclein filaments

7 January 2021

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Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

7 January 2021

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Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome).

7 January 2021

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Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis.

7 January 2021

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Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

7 January 2021

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Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

7 January 2021

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Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

7 January 2021

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NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

7 January 2021

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Neuropathology of Parkinson's disease

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-4886(03)00004-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12710935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference