Brain uptake of Tc99m-HMPAO correlates with clinical response to the novel redox modulating agent EPI-743 in patients with mitochondrial disease (Q48328371)

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scientific article published on 28 September 2012

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English	Brain uptake of Tc99m-HMPAO correlates with clinical response to the novel redox modulating agent EPI-743 in patients with mitochondrial disease	scientific article published on 28 September 2012

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

Brain uptake of Tc99m-HMPAO correlates with clinical response to the novel redox modulating agent EPI-743 in patients with mitochondrial disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

author name string

Francis G Blankenberg

1

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Europe PubMed Central

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10 February 2018

http://europepmc.org/abstract/MED/23084792

Stephen L Kinsman

2

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10 February 2018

http://europepmc.org/abstract/MED/23084792

Bruce H Cohen

3

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10 February 2018

http://europepmc.org/abstract/MED/23084792

Michael L Goris

4

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10 February 2018

http://europepmc.org/abstract/MED/23084792

Kenneth M Spicer

5

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10 February 2018

http://europepmc.org/abstract/MED/23084792

Susan L Perlman

6

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10 February 2018

http://europepmc.org/abstract/MED/23084792

Elliot J Krane

7

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10 February 2018

http://europepmc.org/abstract/MED/23084792

Viktoria Kheifets

8

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PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

Martin Thoolen

9

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

Guy Miller

10

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10 February 2018

http://europepmc.org/abstract/MED/23084792

Gregory M Enns

11

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10 February 2018

http://europepmc.org/abstract/MED/23084792

publication date

28 September 2012

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Europe PubMed Central

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10 February 2018

http://europepmc.org/abstract/MED/23084792

Molecular Genetics and Metabolism

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

107

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PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

4

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PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

690-699

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Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

Pathogenic mitochondrial DNA mutations are common in the general population

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

Mitochondrial respiratory-chain diseases

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

Energetics, epigenetics, mitochondrial genetics

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

Mitochondrial diseases in man and mouse

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7 January 2021

Radical-free biology of oxidative stress

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7 January 2021

Inherited disorders affecting mitochondrial function are associated with glutathione deficiency and hypocitrullinemia

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7 January 2021

Treatment of mitochondrial electron transport chain disorders: a review of clinical trials over the past decade

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7 January 2021

A critical approach to the therapy of mitochondrial respiratory chain and oxidative phosphorylation diseases

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7 January 2021

Animal and human studies with the mitochondria-targeted antioxidant MitoQ.

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7 January 2021

Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria

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(-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

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7 January 2021

Glutathione deficiency in patients with mitochondrial disease: implications for pathogenesis and treatment

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

The retention mechanism of technetium-99m-HM-PAO: intracellular reaction with glutathione

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

The retention of [99mTc]-d,l-HM-PAO in the human brain after intracarotid bolus injection: a kinetic analysis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

Astrocytes as a predominant cellular site of (99m)Tc-HMPAO retention

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

Initial experience in the treatment of inherited mitochondrial disease with EPI-743.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

A scale to monitor progression and treatment of mitochondrial disease in children.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

Mitochondrial disease in adults: a scale to monitor progression and treatment

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

Database of normal human cerebral blood flow measured by SPECT: I. Comparison between I-123-IMP, Tc-99m-HMPAO, and Tc-99m-ECD as referred with O-15 labeled water PET and voxel-based morphometry

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

Magnetic resonance spectroscopy in patients with MELAS.

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7 January 2021

Diagnostic value of proton MR spectroscopy and diffusion-weighted MR imaging in childhood inherited neurometabolic brain diseases and review of the literature

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.09.023

7 January 2021

Initial experiences with proton MR spectroscopy in treatment monitoring of mitochondrial encephalopathy

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7 January 2021

Lactate quantification by proton magnetic resonance spectroscopy using a clinical MRI machine: a basic study

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7 January 2021

PET imaging of redox and energy states in stroke-like episodes of MELAS.

1 reference

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7 January 2021

Cerebral oxygen and glucose metabolism in patients with mitochondrial m.3243A>G mutation

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7 January 2021

Brain energy metabolism in Alzheimer’s disease: 99mTc-HMPAO SPECT imaging during verbal fluency and role of astrocytes in the cellular mechanism of 99mTc-HMPAO retention

1 reference

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7 January 2021

Perfusion status of the stroke-like lesion at the hyperacute stage in MELAS.

1 reference

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7 January 2021

99mTc-propylene amine oxime (99mTc-PnAO); a potential brain radiopharmaceutical

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7 January 2021

Development of a 99Tcm-labelled radiopharmaceutical for cerebral blood flow imaging.

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7 January 2021

Added value of 99mTc-HMPAO-labeled leukocyte SPECT/CT in the characterization and management of patients with infectious endocarditis

1 reference

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7 January 2021

Myoclonus epilepsy and ragged-red fibres (MERRF). 1. A clinical, pathological, biochemical, magnetic resonance spectrographic and positron emission tomographic study

1 reference

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Automated perfusion imaging for the evaluation of transient ischemic attack.

1 reference

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EPI-743 reverses the progression of the pediatric mitochondrial disease--genetically defined Leigh Syndrome.

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7 January 2021

Identifiers

10.1016/J.YMGME.2012.09.023

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 February 2018

http://europepmc.org/abstract/MED/23084792

ResearchGate publication ID

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