Extracellular α-synuclein alters synaptic transmission in brain neurons by perforating the neuronal plasma membrane. (Q48335373)

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29 February 2020

title

Extracellular α-synuclein alters synaptic transmission in brain neurons by perforating the neuronal plasma membrane (English)

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29 February 2020

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8

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29 February 2020

author name string

Carla R Pacheco

1

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29 February 2020

Camila N Morales

2

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29 February 2020

Alejandra E Ramírez

3

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29 February 2020

Francisco J Muñoz

4

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29 February 2020

Scarlet S Gallegos

5

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29 February 2020

Pablo A Caviedes

6

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29 February 2020

Luis G Aguayo

7

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29 February 2020

language of work or name

English

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publication date

25 February 2015

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Journal of Neurochemistry

29 February 2020

number of pages

11

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based on heuristic

inferred from page(s)

published in

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29 February 2020

volume

132

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29 February 2020

issue

6

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29 February 2020

page(s)

731-741

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Neuropsychiatric symptoms in patients with Parkinson's disease and dementia: frequency, profile and associated care giver stress

29 February 2020

cites work

1 reference

Novel one-step immunoassays to quantify α-synuclein: applications for biomarker development and high-throughput screening

21 January 2018

1 reference

Stages in the development of Parkinson's disease-related pathology

21 January 2018

1 reference

Properties of native brain α-synuclein

21 January 2018

1 reference

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

21 January 2018

1 reference

Alpha-synuclein mediates alterations in membrane conductance: a potential role for alpha-synuclein oligomers in cell vulnerability

21 January 2018

1 reference

Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers

21 January 2018

1 reference

Neurodegenerative disease: amyloid pores from pathogenic mutations

21 January 2018

1 reference

The many faces of α-synuclein: from structure and toxicity to therapeutic target

21 January 2018

1 reference

Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons

21 January 2018

1 reference

Calcium and neurodegeneration

21 January 2018

1 reference

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

21 January 2018

1 reference

An extracellular mechanism that can explain the neurotoxic effects of α-synuclein aggregates in the brain

21 January 2018

1 reference

Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

21 January 2018

1 reference

Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure

21 January 2018

1 reference

Biphasic effects of copper on neurotransmission in rat hippocampal neurons.

21 January 2018

1 reference

Inhibition of amyloid beta-induced synaptotoxicity by a pentapeptide derived from the glycine zipper region of the neurotoxic peptide

21 January 2018

1 reference

Amyloid ion channels: a common structural link for protein-misfolding disease

21 January 2018

1 reference

The two-fold aspect of the interplay of amyloidogenic proteins with lipid membranes.

21 January 2018

1 reference

Membrane interactions of oligomeric alpha-synuclein: potential role in Parkinson's disease

21 January 2018

1 reference

Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes

21 January 2018

1 reference

Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property

21 January 2018

1 reference

Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease.

21 January 2018

1 reference

CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.

21 January 2018

1 reference

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

1 reference

γ-Synuclein: seeding of α-synuclein aggregation and transmission between cells

21 January 2018

1 reference

Synucleins: are they two-edged swords?

21 January 2018

1 reference

Early expression of glycine and GABA(A) receptors in developing spinal cord neurons. Effects on neurite outgrowth

21 January 2018

1 reference

Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease.

21 January 2018

1 reference

Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein

21 January 2018

1 reference

Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases

21 January 2018

1 reference

Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation

21 January 2018

1 reference

Vesicle permeabilization by protofibrillar alpha-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism.

21 January 2018

1 reference

Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease

21 January 2018

1 reference

Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus

21 January 2018

1 reference

Structural properties of pore-forming oligomers of alpha-synuclein

21 January 2018

1 reference