The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma. (Q48345594)

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scientific article published in August 2001

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English	The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.	scientific article published in August 2001

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scholarly article

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma. (English)

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

Peter J. Ratcliffe

5

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

author name string

S C Clifford

1

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

D Astuti

2

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

L Hooper

3

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

P H Maxwell

4

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

E R Maher

6

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

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publication date

1 August 2001

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

20

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

36

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

5067-5074

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204602

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Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis.

1 reference

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Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

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Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

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Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

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Chromosome 22q a frequent site of allele loss in head and neck carcinoma

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AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

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Assignment of the hypoxia-inducible factor 1alpha gene to a region of conserved synteny on mouse chromosome 12 and human chromosome 14q

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RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

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Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

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Familial clear cell renal cell carcinoma (FCRC): clinical features and mutation analysis of the VHL, MET, and CUL2 candidate genes

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Activating Smoothened mutations in sporadic basal-cell carcinoma

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Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

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Genomic organization and chromosomal localization of the humanCUL2 gene and the role of von Hippel-Lindau tumor suppressor-binding protein (CUL2 and VBP1) mutation and loss in renal-cell carcinoma development

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LOH at 16p13 is a novel chromosomal alteration detected in benign and malignant microdissected papillary neoplasms of the breast

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Identifiers

10.1038/SJ.ONC.1204602

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

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1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/11526493

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