Functional characterization of chimeric reverse transcriptases with polypeptide subunits of highly divergent HIV-1 group M and O strains. (Q48364835)

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7 November 2019

title

Functional characterization of chimeric reverse transcriptases with polypeptide subunits of highly divergent HIV-1 group M and O strains (English)

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4

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María-José Camarasa

5

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7 November 2019

Luis Menéndez-Arias

1

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author name string

Abraha A

2

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7 November 2019

Quiñones-Mateu ME

3

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7 November 2019

Arts EJ

6

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language of work or name

English

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publication date

15 May 2001

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Journal of Biological Chemistry

7 November 2019

published in

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volume

276

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issue

29

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7 November 2019

page(s)

27470-27479

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Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

7 November 2019

cites work

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Polymerase structures and function: variations on a theme?

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Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV.

21 January 2018

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

21 January 2018

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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

21 January 2018

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Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer

21 January 2018

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The p51 subunit of human immunodeficiency virus type 1 reverse transcriptase is essential in loading the p66 subunit on the template primer

21 January 2018

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p66/p51 and p51/p51 recombinant forms of reverse transcriptase from human immunodeficiency virus type 1--interactions with primer tRNA(Lys3), initiation of cDNA synthesis, and effect of inhibitors

21 January 2018

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Contribution of the p51 subunit of HIV-1 reverse transcriptase to enzyme processivity

21 January 2018

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Human immunodeficiency virus type 1 reverse transcriptase dimer destabilization by 1-[Spiro[4"-amino-2",2" -dioxo-1",2" -oxathiole-5",3'-[2', 5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]]]-3-ethylthy mine

21 January 2018

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Alterations to the primer grip of p66 HIV-1 reverse transcriptase and their consequences for template-primer utilization

21 January 2018

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Analysis of mutations and suppressors affecting interactions between the subunits of the HIV type 1 reverse transcriptase

21 January 2018

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Characterization of the reverse transcriptase of a human immunodeficiency virus type 1 group O isolate.

21 January 2018

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Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115.

21 January 2018

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Studies on the effects of truncating alpha-helix E' of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis.

21 January 2018

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Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance

21 January 2018

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TSAO analogues. Stereospecific synthesis and anti-HIV-1 activity of 1-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro -5''- (4''-amino-1'',2''-oxathiole 2'',2''-dioxide) pyrimidine and pyrimidine-modified nucleosides

21 January 2018

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WHAT IF: a molecular modeling and drug design program

21 January 2018

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A novel neutralization epitope on the 'thumb' subdomain of human immunodeficiency virus type 1 reverse transcriptase revealed by a monoclonal antibody

21 January 2018

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Initiation of (-) strand DNA synthesis from tRNA(3Lys) on lentiviral RNAs: implications of specific HIV-1 RNA-tRNA(3Lys) interactions inhibiting primer utilization by retroviral reverse transcriptases.

21 January 2018

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Drug susceptibility of subtypes A,B,C,D, and E human immunodeficiency virus type 1 primary isolates

21 January 2018

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Enzymatic properties of two mutants of reverse transcriptase of human immunodeficiency virus type 1 (tyrosine 181-->isoleucine and tyrosine 188-->leucine), resistant to nonnucleoside inhibitors

21 January 2018

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The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1

21 January 2018

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Chimeric HIV-1 and feline immunodeficiency virus reverse transcriptases: critical role of the p51 subunit in the structural integrity of heterodimeric lentiviral DNA polymerases

21 January 2018

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21 January 2018

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Conformational stability of dimeric HIV-1 and HIV-2 reverse transcriptases

21 January 2018

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Mutating a region of HIV-1 reverse transcriptase implicated in tRNA(Lys-3) binding and the consequences for (-)-strand DNA synthesis

21 January 2018

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3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors: synthesis and antiviral activity of [2', 5'-bis-O-(tert-butyldimethylsilyl)-.beta.-D-xylo- and -ribofuranose]-3'-spiro-5''-[4''-amino-1'', 2''-oxathiole 2''

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M104342200

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11353775%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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