The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons. (Q48368204)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

Yoshiyuki Konishi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Azad Bonni

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 March 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

1649-1658

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

1 November 2019

cites work

1 reference

12 December 2020

Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

1 reference

12 December 2020

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

1 reference

12 December 2020

Distinct cellular factors regulate the c-myb promoter through its E2F element

1 reference

12 December 2020

Apoptosis and necrosis in cerebrovascular disease

1 reference

12 December 2020

Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

1 reference

12 December 2020

Induction and modulation of cerebellar granule neuron death by E2F-1

1 reference

12 December 2020

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

12 December 2020

Structure and regulation of voltage-gated Ca2+ channels

1 reference

12 December 2020

p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons

1 reference

12 December 2020

Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis

1 reference

12 December 2020

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

1 reference

12 December 2020

Attenuation of neurotoxicity in cortical cultures and hippocampal slices from E2F1 knockout mice.

1 reference

12 December 2020

A dominant negative inhibitor of the Egr family of transcription regulatory factors suppresses cerebellar granule cell apoptosis by blocking c-Jun activation.

1 reference

12 December 2020

Neuronal apoptosis at the G1/S cell cycle checkpoint

1 reference

12 December 2020

Regulation of neuronal survival and death by E2F-dependent gene repression and derepression.

1 reference

12 December 2020

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

1 reference

12 December 2020

N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons.

1 reference

12 December 2020

E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

1 reference

12 December 2020

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

1 reference

12 December 2020

Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery

1 reference

12 December 2020

JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery

1 reference

12 December 2020

Cell cycle regulation of the human cdc2 gene

1 reference

12 December 2020

The E2F transcription factor is a cellular target for the RB protein

1 reference

12 December 2020

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

12 December 2020

Numbers, time and neocortical neuronogenesis: a general developmental and evolutionary model

1 reference

12 December 2020

Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis

1 reference

12 December 2020

Constructing the cerebral cortex: Neurogenesis and fate determination

1 reference

12 December 2020

Mechanisms of neural patterning and specification in the developing cerebellum

1 reference

12 December 2020

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

1 reference

12 December 2020

The retinoblastoma protein and cell cycle control

1 reference

12 December 2020

The G1/S boundary-specific enhancer of the rat cdc2 promoter

1 reference

12 December 2020

Identification of a cell-type-specific and E2F-independent mechanism for repression of cdc2 transcription

1 reference

12 December 2020

Premature p34cdc2 activation required for apoptosis.

1 reference

12 December 2020

Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

1 reference

12 December 2020

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1 reference

12 December 2020

Distinct roles for cyclin-dependent kinases in cell cycle control

1 reference

12 December 2020

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

12 December 2020

In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum

1 reference

12 December 2020

The insulin-like growth factors

1 reference

12 December 2020

In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression

1 reference

12 December 2020

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

1 reference

12 December 2020

Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells.

1 reference

12 December 2020

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

12 December 2020

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

12 December 2020

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

1 reference

12 December 2020

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain.

1 reference

12 December 2020

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

12 December 2020

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

1 reference

12 December 2020

Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

1 reference

12 December 2020

Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain.

1 reference

12 December 2020

Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

1 reference

12 December 2020

1 reference

12 December 2020

The regulation of E2F by pRB-family proteins

1 reference

12 December 2020

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

1 reference

12 December 2020

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

12 December 2020

10.1523/JNEUROSCI.23-05-01649.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12629169%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference