Obtaining evidence by a single well-powered trial or several modestly powered trials. (Q48371779)

11 February 2018

title

Obtaining evidence by a single well-powered trial or several modestly powered trials. (English)

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11 February 2018

2

John Pa Ioannidis

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11 February 2018

author name string

Joanna IntHout

series ordinal

1

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11 February 2018

George F Borm

series ordinal

3

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11 February 2018

publication date

14 October 2012

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11 February 2018

Statistical Methods in Medical Research

published in

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11 February 2018

volume

25

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issue

2

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11 February 2018

page(s)

538-552

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11 February 2018

Sample size calculations in randomised trials: mandatory and mystical

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The continuing unethical conduct of underpowered clinical trials.

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Publication bias was not a good reason to discourage trials with low power.

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Reasons or excuses for avoiding meta-analysis in forest plots

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Mega-trials vs. meta-analysis: Precision vs. heterogeneity?

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Contradicted and initially stronger effects in highly cited clinical research

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Measuring inconsistency in meta-analyses

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Uncertainty in heterogeneity estimates in meta-analyses

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Trial publication after registration in ClinicalTrials.Gov: a cross-sectional analysis

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Publication of clinical trials supporting successful new drug applications: a literature analysis

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Systematic review of the empirical evidence of study publication bias and outcome reporting bias

21 January 2018

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Extent of publication bias in different categories of research cohorts: a meta-analysis of empirical studies

21 January 2018

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Reporting bias in drug trials submitted to the Food and Drug Administration: review of publication and presentation

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Meta-analysis in clinical trials

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A simple confidence interval for meta-analysis.

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A comparison of statistical methods for meta-analysis

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Confidence intervals for random effects meta-analysis and robustness to publication bias.

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Where now for meta-analysis?

21 January 2018

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Comparing results from meta-analyses vs large trials.

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Generalizing results of randomized trials to clinical practice: reliability and cautions

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21 January 2018

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Small clinical trials: are they all bad?

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Systematic reviews in health care: Assessing the quality of controlled clinical trials

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The effects of exercise on falls in elderly patients. A preplanned meta-analysis of the FICSIT Trials. Frailty and Injuries: Cooperative Studies of Intervention Techniques.

21 January 2018

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Short-term outcome after stenting versus endarterectomy for symptomatic carotid stenosis: a preplanned meta-analysis of individual patient data

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Comparative effectiveness research: who will do the studies?

21 January 2018

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21 January 2018

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Updating meta-analyses leads to larger type I errors than publication bias

21 January 2018

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Why are so few randomized trials useful, and what can we do about it?

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/0962280212461098

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11 February 2018

PubMed ID

23070590

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11 February 2018