The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouse. (Q48372864)
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scientific article published on 10 November 2006
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouse. |
scientific article published on 10 November 2006 |
Statements
The novel gamma secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) reduces amyloid plaque deposition without evidence of notch-related pathology in the Tg2576 mouse (English)
Jonathan D Best
David W Smith
Michael A Reilly
Ruth O'Donnell
Huw D Lewis
Semantha Ellis
Neil Wilkie
Thomas W Rosahl
Philippe A Laroque
Christine Boussiquet-Leroux
Ian Churcher
Timothy Harrison
Mark S Shearman
10 November 2006