Genomic organization of the genes encoding mouse T-cell receptor alpha-chain. (Q48376436)

11 February 2018

title

Genomic organization of the genes encoding mouse T-cell receptor alpha-chain. (English)

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11 February 2018

author name string

Winoto A

series ordinal

1

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11 February 2018

Mjolsness S

series ordinal

2

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11 February 2018

Hood L

series ordinal

3

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11 February 2018

language of work or name

English

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publication date

1 August 1985

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11 February 2018

published in

Nature

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11 February 2018

volume

316

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11 February 2018

issue

6031

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11 February 2018

page(s)

832-836

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11 February 2018

https://scigraph.springernature.com/pub.10.1038/316832a0

exact match

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cites work

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The human T cell antigen receptor is encoded by variable, diversity, and joining gene segments that rearrange to generate a complete V gene

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The structure, rearrangement and expression of Dβ gene segments of the murine T-cell antigen receptor

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Somatic recombination in a murine T-cell receptor gene

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Genomic organization and sequence of T-cell receptor beta-chain constant- and joining-region genes.

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Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

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A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

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A third type of murine T-cell receptor gene

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A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

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Primary structure of human T-cell receptor alpha-chain

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Diversity and structure of genes of the α family of mouse T-cell antigen receptor

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An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

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Organization and expression of eucaryotic split genes coding for proteins

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The T cell receptor beta chain genes are located on chromosome 6 in mice and chromosome 7 in humans

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Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions

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The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments.

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Antibody diversity: somatic hypermutation of rearranged VH genes

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IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts

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Sequences at the somatic recombination sites of immunoglobulin light-chain genes

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Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes.

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A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene.

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A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes.

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Immunoglobulin gene transcription is activated by downstream sequence elements

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High-Efficiency Cloning of Full-Length cDNA

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57 Sequencing end-labeled DNA with base-specific chemical cleavages

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Organization of the constant-region gene family of the mouse immunoglobulin heavy chain

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Unusual organization and diversity of T-cell receptor alpha-chain genes.

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Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor alpha-chain.

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Identifiers

DOI

10.1038/316832A0

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11 February 2018

Dimensions Publication ID

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11 February 2018