The tachykinin NK1 receptor antagonist GR205171 prevents vagal stimulation-induced retching but not neuronal transmission from emetic vagal afferents to solitary nucleus neurons in dogs. (Q48389709)

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scientific article published in August 1998

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English	The tachykinin NK1 receptor antagonist GR205171 prevents vagal stimulation-induced retching but not neuronal transmission from emetic vagal afferents to solitary nucleus neurons in dogs.	scientific article published in August 1998

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scholarly article

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

The tachykinin NK1 receptor antagonist GR205171 prevents vagal stimulation-induced retching but not neuronal transmission from emetic vagal afferents to solitary nucleus neurons in dogs. (English)

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

tachykinin receptor

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author name string

H Fukuda

1

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

T Koga

2

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

N Furukawa

3

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

E Nakamura

4

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

Y Shiroshita

5

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

language of work or name

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publication date

1 August 1998

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11 February 2018

http://europepmc.org/abstract/MED/9748589

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

802

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1-2

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221-231

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http://europepmc.org/abstract/MED/9748589

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NMDA receptor-independent mechanisms responsible for the rate of rise of cumulative depolarization evoked by trains of dorsal root stimuli on rat spinal motoneurones.

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Converse motor output of inspiratory bulbospinal premotoneurones during vomiting

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Anti-emetic profile of a non-peptide neurokinin NK1 receptor antagonist, CP-99,994, in ferrets

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Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation

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The Bötzinger complex as the pattern generator for retching and vomiting in the dog

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Non-respiratory neurons in the Bötzinger complex exhibiting appropriate firing patterns to generate the emetic act in dogs

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Hypercapnia and hypoxia which develop during retching participate in the transition from retching to expulsion in dogs.

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Activation of peripheral and/or central chemoreceptors changes retching activities of Bötzinger complex neurons and induces expulsion in decerebrate dogs

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Differential effects of capsaicin on the content of somatostatin, substance P, and neurotensin in the nervous system of the rat

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The broad-spectrum anti-emetic activity of the novel non-peptide tachykinin NK1 receptor antagonist GR203040

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GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity

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Activity of respiratory-related oropharyngeal and laryngeal motoneurones during fictive vomiting in the decerebrate cat.

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Immunohistochemical study of neuropeptides in vagal and glossopharyngeal afferent neurons in the rat.

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Discharge patterns of bulbar respiratory neurons during retching and vomiting in decerebrate dogs

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Characteristic behavior of the respiratory muscles, esophagus, and external anal and urethral sphincters during straining, retching, and vomiting in the decerebrate dog.

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Neurons in the nucleus of the solitary tract mediating inputs from emetic vagal afferents and the area postrema to the pattern generator for the emetic act in dogs

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7 January 2021

Bulbospinal augmenting inspiratory neurons may participate in contractions of the diaphragm during vomiting in decerebrate dogs

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Descending pathway from the central pattern generator of vomiting.

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Control of abdominal and expiratory intercostal muscle activity during vomiting: role of ventral respiratory group expiratory neurons

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Behavior of inhibitory and excitatory propriobulbar respiratory neurons during fictive vomiting

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Wind-up and the NMDA receptor: from animal studies to humans

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Capsaicin in the 4th ventricle abolishes retching and transmission of emetic vagal afferents to solitary nucleus neurons.

1 reference

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7 January 2021

Rate of rise of the cumulative depolarization evoked by repetitive stimulation of small-caliber afferents is a predictor of action potential windup in rat spinal neurons in vitro.

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7 January 2021

Capsaicin application to central or peripheral vagal fibers attenuates CCK satiety

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The tachykinin NK1 receptor antagonist CP-99,994 attenuates cisplatin induced emesis in the ferret

1 reference

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Enantioselective inhibition of apomorphine-induced emesis in the ferret by the neurokinin1 receptor antagonist CP-99,994

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Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets

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Immunohistochemical and biochemical analysis of serotonin and substance P colocalization in the nucleus tractus solitarii and associated afferent ganglia of the rat.

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7 January 2021

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10.1016/S0006-8993(98)00630-1

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/9748589

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