Perforin-dependent neurologic injury in a viral model of multiple sclerosis. (Q48395919)

http://europepmc.org/abstract/MED/9736651

11 February 2018

title

Perforin-dependent neurologic injury in a viral model of multiple sclerosis (English)

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12 May 2020

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2

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12 May 2020

author name string

P D Murray

1

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12 May 2020

X Lin

3

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12 May 2020

M K Njenga

4

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12 May 2020

J Leibowitz

5

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L R Pease

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793251&resulttype=core&format=json

12 May 2020

M Rodriguez

7

1 reference

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12 May 2020

language of work or name

English

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publication date

1 September 1998

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http://europepmc.org/abstract/MED/9736651

11 February 2018

published in

Journal of Neuroscience

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12 May 2020

volume

18

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12 May 2020

issue

18

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12 May 2020

page(s)

7306-7314

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Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain

12 May 2020

cites work

1 reference

12 December 2020

Imaging Ca2+ changes in individual oligodendrocytes attacked by T-cell perforin

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12 December 2020

Demyelination induced by Theiler's virus: influence of the H-2 haplotype

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12 December 2020

Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene

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12 December 2020

Mice lacking MHC class II molecules

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12 December 2020

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

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12 December 2020

VP1 and VP2 capsid proteins of Theiler's virus are targets of H-2D-restricted cytotoxic lymphocytes in the central nervous system of B10 mice

1 reference

12 December 2020

Role of natural killer cells as immune effectors in encephalitis and demyelination induced by Theiler's virus

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12 December 2020

The roles of perforin- and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses

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12 December 2020

A low-cost method to analyse footprint patterns

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12 December 2020

Multiple sclerosis: oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis.

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12 December 2020

Persistent infection of oligodendrocytes in Theiler's virus‐induced encephalomyelitis

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12 December 2020

Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice

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12 December 2020

Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice

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12 December 2020

Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV-specific delayed-type hypersensitivity

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12 December 2020

Measurement of atactic and paretic gait in neuropathies of rats based on analysis of walking tracks

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12 December 2020

Characterization of the inflammatory response in the central nervous system of mice susceptible or resistant to demyelination by Theiler's virus

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12 December 2020

Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors

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12 December 2020

Decreased tumor surveillance in perforin-deficient mice

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12 December 2020

Oligodendrocyte susceptibility to injury by T-cell perforin

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12 December 2020

Multiple sclerosis: Fas signaling in oligodendrocyte cell death

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12 December 2020

Spontaneous CNS remyelination in beta 2 microglobulin-deficient mice following virus-induced demyelination.

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12 December 2020

Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis

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12 December 2020

Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo

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12 December 2020

An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks

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12 December 2020

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

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12 December 2020

Identification of an astrocyte cell population from human brain that expresses perforin, a cytotoxic protein implicated in immune defense

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12 December 2020

Neonatal infection with the Daniels strain of Theiler's murine encephalomyelitis virus

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12 December 2020

Reorganization of the Axon Membrane in Demyelinated Peripheral Nerve Fibers: Morphological Evidence

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12 December 2020

Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway

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12 December 2020

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

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12 December 2020

Molecular cloning and sequence determination of DA strain of Theiler's murine encephalomyelitis viruses

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12 December 2020

Demyelinative myelopathy in mice induced by the DA virus

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12 December 2020

Immune function in mice lacking the perforin gene

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12 December 2020

Neurons induced to express major histocompatibility complex class I antigen are killed via the perforin and not the Fas (APO-1/CD95) pathway

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12 December 2020

10.1523/JNEUROSCI.18-18-07306.1998

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793251&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793251&resulttype=core&format=json

12 May 2020

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