Immunohistochemical markers for prognosis of cerebral glioblastomas (Q48505519)

12 February 2018

title

Immunohistochemical markers for prognosis of cerebral glioblastomas (English)

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12 February 2018

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1

Andrey Korshunov

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12 February 2018

author name string

Andrey Golanov

series ordinal

2

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12 February 2018

Regina Sycheva

series ordinal

3

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12 February 2018

publication date

1 July 2002

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12 February 2018

Journal of Neuro-Oncology

published in

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12 February 2018

volume

58

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12 February 2018

issue

3

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12 February 2018

page(s)

217-236

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12 February 2018

Prognostic significance of Ki67, p53 and epidermal growth factor receptor immunostaining in human glioblastomas.

cites work

1 reference

12 December 2020

Relationships between Ki-67 labelling index, amplification of the epidermal growth factor receptor gene, and prognosis in human glioblastomas

1 reference

12 December 2020

Apoptosis in astrocytomas with different grades of malignancy

1 reference

12 December 2020

Bcl-2 distribution in neuroepithelial tumors: an immunohistochemical study.

1 reference

12 December 2020

In situ hybridization with single-stranded RNA probes to demonstrate infrequently elevated gli mRNA and no increased ras mRNA levels in meningiomas and astrocytomas

1 reference

12 December 2020

Developmental changes in the cellular distribution of glutathione and glutathione S-transferases in the murine nervous system.

1 reference

12 December 2020

Histologic factors of prognostic significance in the glioblastoma multiforme

1 reference

12 December 2020

Necrosis as a prognostic factor in glioblastoma multiforme.

1 reference

12 December 2020

TP53 gene mutations, nuclear p53 accumulation, expression of Waf/p21, Bcl-2, and CD95 (APO-1/Fas) proteins are not prognostic factors in de novo glioblastoma multiforme

1 reference

12 December 2020

Survival of patients with glioblastoma multiforme is not influenced by altered expression of p16, p53, EGFR, MDM2 or Bcl-2 genes

1 reference

12 December 2020

Bromodeoxyuridine labeling index in glioblastoma multiforme: relation to radiation response, age, and survival.

1 reference

12 December 2020

Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas

1 reference

12 December 2020

Amplification of Epidermal Growth Factor Receptor Gene in Gliomas: Histopathology and Prognosis

1 reference

12 December 2020

Epidermal growth factor receptor and labeling index are independent prognostic factors in glial tumor outcome.

1 reference

12 December 2020

Akt pathway activation converts anaplastic astrocytoma to glioblastoma multiforme in a human astrocyte model of glioma.

1 reference

12 December 2020

Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients.

1 reference

12 December 2020

Lack of prognostic relevance of alterations in the epidermal growth factor receptor-transforming growth factor-alpha pathway in human astrocytic gliomas.

1 reference

12 December 2020

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

1 reference

12 December 2020

Apoptosis in astrocytic neoplasms.

1 reference

12 December 2020

Genetic alterations in adult diffuse glioma: occurrence, significance, and prognostic implications

1 reference

12 December 2020

Correlation of tumor p53 and PCNA with response and survival of glioblastoma in patients treated with an ECOG protocol of pre-irradiation chemotherapy.

1 reference

12 December 2020

Aberrant p53, mdm2, and proliferation differ in glioblastomas from long-term compared with typical survivors.

1 reference

12 December 2020

Long-term glioblastoma multiforme survivors: a population-based study.

1 reference

12 December 2020

Prognostic implications of p53 overexpression in supratentorial astrocytic tumors.

1 reference

12 December 2020

Polymorphism in glutathione S-transferase loci as a risk factor for common cancers

1 reference

12 December 2020

Aberrant p21 regulation in radioresistant primary glioblastoma multiforme cells bearing wild-type p53.

1 reference

12 December 2020

MDM2 and p53 expression in gliomas: a multivariate survival analysis including proliferation markers and epidermal growth factor receptor

1 reference

12 December 2020

BCL-2 family protein expression in human malignant glioma: a clinical-pathological correlative study

1 reference

12 December 2020

Molecular analysis of the PTEN, TP53 and CDKN2A tumor suppressor genes in long-term survivors of glioblastoma multiforme.

1 reference

12 December 2020

Prognostic significance of p53 immunoreactivity in adult patients with supratentorial fibrillary astrocytic neoplasms.

1 reference

12 December 2020

Sporadic p53 mutations and absence of ras mutations in glioblastomas.

1 reference

12 December 2020

Long-term survival of glioblastoma multiforme: importance of histopathological reevaluation.

1 reference

12 December 2020

Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas

1 reference

12 December 2020

Epidermal growth factor receptor activity and clinical outcome in glioblastoma and meningioma

1 reference

12 December 2020

Analysis of 2 antiapoptotic factors in gliomas: bcl-2 overexpression and p53 mutations.

1 reference

12 December 2020

The epidermal growth factor receptor in glioblastoma: genomic amplification, protein expression, and patient survival data in a therapeutic trial.

1 reference

12 December 2020

Histopathologic and immunohistochemical prognostic factors in malignant gliomas

1 reference

12 December 2020

Immunohistochemical staining of DNA topoisomerase IIalpha in human gliomas

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12 December 2020

Distinct radiochemotherapy protocols differentially influence cellular proliferation and expression of p53 and Bcl-2 in glioblastoma multiforme relapses in vivo.

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12 December 2020

p53 function influences the effect of fractionated radiotherapy on glioblastoma tumors

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12 December 2020

Expression of bcl-2 in reactive and neoplastic astrocytes: lack of correlation with presence or degree of malignancy.

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12 December 2020

Prognostic relevance of epidermal growth factor receptor (EGF-R) and c-neu/erbB2 expression in glioblastomas (GBMs).

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12 December 2020

Gene amplification as a prognostic factor in primary brain tumors

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12 December 2020

Amplification and overexpression of MDM2 in primary (de novo) glioblastomas.

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12 December 2020

Subsets of glioblastoma multiforme defined by molecular genetic analysis

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12 December 2020

The role of growth factor receptors in central nervous system development and neoplasia

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12 December 2020

Long-term survivors of glioblastoma multiforme: clinical and molecular characteristics.

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12 December 2020

Prognostic significance of endothelial surface score and MIB-1 labeling index in glioblastoma.

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12 December 2020

Histologic and non-histologic factors correlated with survival time in supratentorial astrocytic tumors

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12 December 2020

Long-term survival in patients with glioblastoma multiforme

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12 December 2020

Chromosomal abnormalities in glioblastoma multiforme by comparative genomic hybridization: correlation with radiation treatment outcome.

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12 December 2020

Malignant glioma: genetics and biology of a grave matter.

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12 December 2020

Apoptosis in cerebral astrocytic tumours and its relationship to expression of the bcl-2 and p53 proteins.

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12 December 2020

Mitogenic signaling and the relationship to cell cycle regulation in astrocytomas.

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12 December 2020

Induction of apoptosis in multi-drug resistant (MDR) human glioblastoma cells by SN-38, a metabolite of the camptothecin derivative CPT-11.

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12 December 2020

The prognostic value of tumor markers in patients with glioblastoma multiforme: analysis of 32 patients and review of the literature

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12 December 2020

Immunohistochemical expression of P-glycoprotein and glutathione S-transferases in cerebral gliomas and response to chemotherapy

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12 December 2020

Small cell architecture--a histological equivalent of EGFR amplification in glioblastoma multiforme?

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12 December 2020

Preferential expression of Fas/APO1 (CD95) and apoptotic cell death in perinecrotic cells of glioblastoma multiforme.

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12 December 2020

Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications

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12 December 2020

Epidermal growth factor receptor: an independent predictor of survival in astrocytic tumors given definitive irradiation

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12 December 2020

DNA topoisomerase II-alpha as a proliferation marker in astrocytic neoplasms of the central nervous system: correlation with MIB1 expression and patient survival.

1 reference

12 December 2020

Correlations between cytologic composition and biologic behavior in the glioblastoma multiforme. A postmortem study of 50 cases

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12 December 2020

Proliferating cell nuclear antigen expression in the survival of astrocytoma patients.

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12 December 2020

Pathologic significance of proliferative activity and oncoprotein expression in astrocytic tumors.

1 reference

12 December 2020

Apoptosis in glial tumors as determined by in situ nonradioactive labeling of DNA breaks.

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12 December 2020

PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.

1 reference

12 December 2020

Age and radiation response in glioblastoma multiforme.

1 reference

12 December 2020

Patient age, histologic features, and length of survival in patients with glioblastoma multiforme.

1 reference

12 December 2020

Prognostication of astrocytoma patient survival by Ki-67 (MIB-1), PCNA, and S-phase fraction using archival paraffin-embedded samples

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12 December 2020

Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis.

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12 December 2020

Drug resistance in brain tumors

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12 December 2020

Biological evaluation of biopsies from adult cerebral astrocytomas: cell-growth/cell-suicide ratios and their relationship to patient survival

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12 December 2020

Correlation of proliferating cell nuclear antigen assessment, histologic parameters and age with survival in patients with glioblastoma multiforme.

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12 December 2020

Selective sensitivity to radiation of cerebral glioblastomas harboring p53 mutations

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12 December 2020

Quantitative telomerase expression in glioblastomas shows regional variation and down-regulation with therapy but no correlation with patient outcome.

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12 December 2020

Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumours

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12 December 2020

The intrinsic radioresistance of glioblastoma-derived cell lines is associated with a failure of p53 to induce p21(BAX) expression

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12 December 2020

Prognostic factors in astrocytomas: relationship of p53, MDM-2, BCL-2 and PCNA immunohistochemical expression to tumor grade and overall patient survival.

1 reference

12 December 2020

Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR.

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12 December 2020

p53 immunoreactivity in astrocytomas and its relationship to survival

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12 December 2020

Proliferating cell nuclear antigen immunostaining and survival in cerebral astrocytoma

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12 December 2020

How can we prevent cancer?

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12 December 2020

Loss of DCC expression in astrocytomas: relation to p53 abnormalities, cell kinetics, and survival

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12 December 2020

Glioblastoma multiforme and anaplastic astrocytoma. Pathologic criteria and prognostic implications

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12 December 2020

EGFR overexpression and radiation response in glioblastoma multiforme

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12 December 2020

Correlation of p53 immunoreactivity and sequencing in patients with glioma.

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12 December 2020

Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma

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12 December 2020

Amplification of the epidermal-growth-factor-receptor gene correlates with different growth behaviour in human glioblastoma.

1 reference

12 December 2020

p53 immunohistochemical positivity as a prognostic marker in intracranial tumours.

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12 December 2020

Apoptosis in neurological disease

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12 December 2020

Prognostic factors in gliomas. A multivariate analysis of clinical, pathologic, flow cytometric, cytogenetic, and molecular markers

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12 December 2020

Glutathione S-transferases and gamma-glutamyl transpeptidase in the rat nervous systems: a basis for differential susceptibility to neurotoxicants

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12 December 2020

Short alternative splice transcripts of the mdm2 oncogene correlate to malignancy in human astrocytic neoplasms

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12 December 2020

Glioma classification: a molecular reappraisal

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12 December 2020

bcl-2 protein expression in tumors of the central nervous system

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12 December 2020

High cyclin E/low p27Kip1 expression is associated with poor prognosis in astrocytomas.

1 reference

12 December 2020

Prognostic significance of Ki-67 proliferation index in supratentorial fibrillary astrocytic neoplasms

1 reference

12 December 2020

Expression of epidermal growth factor receptor in human glioblastoma multiforme

1 reference

12 December 2020

Necrogenesis and Fas/APO-1 (CD95) expression in primary (de novo) and secondary glioblastomas

1 reference

12 December 2020

Genetic sub-types of human malignant astrocytoma correlate with survival

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12 December 2020

A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis

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12 December 2020

Analysis of proliferation markers and p53 expression in gliomas of astrocytic origin: relationships and prognostic value.

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12 December 2020

Chromosome 11p15 deletions in human malignant astrocytomas and primitive neuroectodermal tumors

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12 December 2020

Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas.

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12 December 2020

Extent of resection as a prognostic variable in the treatment of gliomas

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12 December 2020

Primary and secondary glioblastomas: from concept to clinical diagnosis

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12 December 2020

Analysis of proliferation and apoptosis in brain gliomas: prognostic and clinical value

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12 December 2020

Prognostic indicators in a range of astrocytic tumours: an immunohistochemical study with Ki-67 and p53 antibodies.

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12 December 2020

Long-term survival after the diagnosis of malignant glioma: a series of 22 patients surviving more than 4 years after diagnosis

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12 December 2020

p53 status has no prognostic significance in glioblastomas treated with radiotherapy.

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12 December 2020

A study of apoptosis in normal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks

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12 December 2020

Treatment of patients with primary glioblastoma multiforme with standard postoperative radiotherapy and radiosurgical boost: prognostic factors and long-term outcome

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12 December 2020

Apoptosis: implications of basic research for clinical oncology

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12 December 2020

Distribution of epidermal growth factor receptor gene amplification in brain tumours and correlation to prognosis.

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12 December 2020

Statistical modelling in analysis of prognosis in glioblastoma multiforme: a study of clinical variables and Ki-67 index

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12 December 2020

The challenge of p53 as prognostic and predictive factor in gliomas

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12 December 2020

ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture.

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12 December 2020

Prognostic factors in malignant glioma: influence of the overexpression of oncogene and tumor-suppressor gene products on survival.

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12 December 2020

Apoptosis and prognosis in cancer: rationale and relevance.

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12 December 2020

The role of tumor resection in the treatment of glioblastoma multiforme in adults.

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12 December 2020

Prognostic significance of glutathione S-transferase pi expression and subcellular localization in human gliomas

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12 December 2020

A comparative study of apoptosis and proliferation in germinoma and glioblastoma

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12 December 2020

A study of apoptosis in brain tumors by in situ end-labeling method.

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12 December 2020

Clinical evidence of distinct subgroups of astrocytic tumors defined by comparative genomic hybridization.

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12 December 2020

Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification

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12 December 2020

In contrast to EGFr gene overexpression, H-ras gene expression decreases in human gliomas

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12 December 2020

p53-dependent G1 arrest and p53-independent apoptosis influence the radiobiologic response of glioblastoma

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12 December 2020

Localization of apoptotic cells in situ of brain tumors

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12 December 2020

Expression of activated epidermal growth factor receptors, Ras-guanosine triphosphate, and mitogen-activated protein kinase in human glioblastoma multiforme specimens

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12 December 2020

Detection of apoptotic cells in archival tissue from diffuse astrocytomas using a monoclonal antibody to single-stranded DNA.

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12 December 2020

Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin

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12 December 2020

Long-term survival in patients with malignant astrocytoma

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12 December 2020

A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival

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12 December 2020

Identifiers

DOI

10.1023/A:1016218117251

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12 February 2018

Dimensions Publication ID

1017474734

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12 February 2018