Unmet challenges in immune-mediated hepatobiliary diseases (Q48542369)

12 February 2018

title

Unmet challenges in immune-mediated hepatobiliary diseases (English)

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12 February 2018

2

M Eric Gershwin

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12 February 2018

Ulrich Beuers

1

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12 February 2018

publication date

1 June 2015

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12 February 2018

Clinical Reviews in Allergy & Immunology

published in

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12 February 2018

volume

48

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12 February 2018

issue

2-3

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12 February 2018

page(s)

127-131

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12 February 2018

Myasthenia Gravis: paradox versus paradigm in autoimmunity

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The critical importance of epigenetics in autoimmunity

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Breach of tolerance: primary biliary cirrhosis

21 January 2018

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Differential modulation by IL-17A of Cholangitis versus Colitis in IL-2Rα deleted mice

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Whole-genome DNA methylation in skin lesions from patients with psoriasis vulgaris

21 January 2018

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The immunobiology and pathophysiology of primary biliary cirrhosis

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Immunization with hepatitis B vaccine accelerates SLE-like disease in a murine model

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Drug-induced autoimmune liver disease: A diagnostic dilemma of an increasingly reported disease.

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Antimitochondrial antibody heterogeneity and the xenobiotic etiology of primary biliary cirrhosis

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Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils

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Drug-induced liver injury with autoimmune features

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Compromised central tolerance of ICA69 induces multiple organ autoimmunity.

21 January 2018

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FOXP3: genetic and epigenetic implications for autoimmunity

21 January 2018

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Environment and primary biliary cirrhosis: electrophilic drugs and the induction of AMA.

21 January 2018

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Epigenetic considerations and the clinical reevaluation of the overlap syndrome between primary biliary cirrhosis and autoimmune hepatitis

21 January 2018

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DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype.

21 January 2018

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Engineering of synthetic cellular microenvironments: implications for immunity

21 January 2018

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Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse

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The diagnosis of primary biliary cirrhosis

21 January 2018

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Innate immunity drives xenobiotic-induced murine autoimmune cholangitis

21 January 2018

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Experimental Autoimmune Myasthenia Gravis (EAMG): from immunochemical characterization to therapeutic approaches

21 January 2018

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Autoimmune hepatitis: 50 Years of (slow) progress

21 January 2018

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Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells

21 January 2018

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The role of natural killer cells in autoimmune liver disease: a comprehensive review

21 January 2018

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Pathway-based analysis of primary biliary cirrhosis genome-wide association studies

21 January 2018

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Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis

21 January 2018

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Clonality, activated antigen-specific CD8(+) T cells, and development of autoimmune cholangitis in dnTGFβRII mice

21 January 2018

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Halothane-induced hepatitis: paradigm or paradox for drug-induced liver injury

21 January 2018

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Y chromosome loss in male patients with primary biliary cirrhosis.

21 January 2018

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Shotgun proteomics: identification of unique protein profiles of apoptotic bodies from biliary epithelial cells

21 January 2018

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Few Foxp3⁺ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity.

21 January 2018

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Prometheus unbound: NKT cells inhibit hepatic regeneration

21 January 2018

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Novel approaches to the development of targeted therapeutic agents for systemic lupus erythematosus.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Successful immunotherapy of autoimmune cholangitis by adoptive transfer of forkhead box protein 3(+) regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Antimitochondrial antibody recognition and structural integrity of the inner lipoyl domain of the E2 subunit of pyruvate dehydrogenase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Animal models of primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

CXCR5+ CD4+ T follicular helper cells participate in the pathogenesis of primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: implications for therapy

21 January 2018

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Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2Rα(-/-) mice

21 January 2018

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Ongoing activation of autoantigen-specific B cells in primary biliary cirrhosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Primary biliary cirrhosis

21 January 2018

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EASL Clinical Practice Guidelines: management of cholestatic liver diseases.

21 January 2018

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Epidemiology of primary sclerosing cholangitis and primary biliary cirrhosis: a systematic review

21 January 2018

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Genetics in PBC: what do the "risk genes" teach us?

21 January 2018

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Multiple genetic variants associated with primary biliary cirrhosis in a Han Chinese population

21 January 2018

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The causes of primary biliary cirrhosis: Convenient and inconvenient truths

21 January 2018

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The biliary HCO(3)(-) umbrella: a unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Mechanisms of tissue injury in autoimmune liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Animal models in primary biliary cirrhosis and primary sclerosing cholangitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

The coexistence of Sjögren's syndrome and primary biliary cirrhosis: a comprehensive review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Women and primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Pregnancy and primary biliary cirrhosis: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Biochemical response to ursodeoxycholic acid and long-term prognosis in primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Levels of alkaline phosphatase and bilirubin are surrogate end points of outcomes of patients with primary biliary cirrhosis: an international follow-up study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Excellent long-term survival in patients with primary biliary cirrhosis and biochemical response to ursodeoxycholic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

New therapies for primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Novel therapeutic targets in primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

New paradigms in the treatment of hepatic cholestasis: from UDCA to FXR, PXR and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Pathogenesis of primary biliary cirrhosis and its fatigue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Pruritus in cholestasis: facts and fiction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Genetics in PSC: what do the "risk genes" teach us?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Genome-wide association analysis in primary sclerosing cholangitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Characterization of animal models for primary sclerosing cholangitis (PSC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Diagnosis and management of primary sclerosing cholangitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Immunoglobulin G4+ clones identified by next-generation sequencing dominate the B cell receptor repertoire in immunoglobulin G4 associated cholangitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Plasmablasts as a biomarker for IgG4-related disease, independent of serum IgG4 concentrations

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Exposure to occupational antigens might predispose to IgG4-related disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjögren's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

New therapeutics in primary biliary cirrhosis: will there ever be light?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Outcome measures for primary Sjögren's syndrome: a comprehensive review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Genome-Wide Association Study Identifies Variants Associated With Autoimmune Hepatitis Type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-015-8484-9

Extrahepatic malignancies in primary biliary cirrhosis: a comparative study at two European centers

21 January 2018

1 reference

12 December 2020

TGR5: pathogenetic role and/or therapeutic target in fibrosing cholangitis?

1 reference

12 December 2020

Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis

1 reference

12 December 2020

Autoimmunity and antibody affinity maturation are modulated by genetic variants on mouse chromosome 12.

1 reference

12 December 2020

Early primary biliary cirrhosis: biochemical response to treatment and prediction of long-term outcome

1 reference

12 December 2020

Genetic Risks Link Autoimmune Hepatitis to Other Autoimmune Liver Disease

1 reference

12 December 2020

Retention and tolerance of autoreactive CD4(+) recent thymic emigrants in the liver

1 reference

12 December 2020

Decreased anion exchanger 2 immunoreactivity in the liver of patients with primary biliary cirrhosis

1 reference

12 December 2020

Fucosyltransferase 2: a genetic risk factor for primary sclerosing cholangitis and Crohn's disease--a comprehensive review

1 reference

12 December 2020

Loss of CD28 expression by liver-infiltrating T cells contributes to pathogenesis of primary sclerosing cholangitis

1 reference

12 December 2020

10.1007/S12016-015-8484-9

Identifiers

DOI

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12 February 2018

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12 February 2018