Serial analysis of gene expression identifies metallothionein-II as major neuroprotective gene in mouse focal cerebral ischemia. (Q48546198)

PubMed publication ID

12122050

12 February 2018

http://europepmc.org/abstract/MED/12122050

title

Serial analysis of gene expression identifies metallothionein-II as major neuroprotective gene in mouse focal cerebral ischemia (English)

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Ulrich Dirnagl

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Andreas Meisel

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12 May 2020

author name string

George Trendelenburg

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Konstantin Prass

2

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Krisztian Kapinya

4

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Andreas Polley

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Claudia Muselmann

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Karsten Ruscher

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Ute Kannbley

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Armin O Schmitt

9

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Stefanie Castell

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Frank Wiegand

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Andre Rosenthal

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language of work or name

English

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publication date

1 July 2002

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PubMed publication ID

12122050

12 February 2018

http://europepmc.org/abstract/MED/12122050

published in

Journal of Neuroscience

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volume

22

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12 May 2020

issue

14

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12 May 2020

page(s)

5879-5888

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CNS wound healing is severely depressed in metallothionein I- and II-deficient mice.

12 May 2020

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Evidence for a protective role of metallothionein-1 in focal cerebral ischemia

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69 Overview of metallothionein

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Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals

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Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination

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Inhibition of cell membrane lipid peroxidation by cadmium- and zinc-metallothioneins

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Regulation, Linkage, and Sequence of Mouse Metallothionein I and II Genes

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Cloning and sequencing of cDNA for mouse liver metallothionein-I

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Structure of mouse metallothionein-I gene and its mRNA.

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12 December 2020

Serial analysis of gene expression

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12 December 2020

Expression and regulation of brain metallothionein

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Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

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Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium

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Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase

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Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats

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Metallothionein I and II protect against zinc deficiency and zinc toxicity in mice

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A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

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Immunocytochemically detectable metallothionein is expressed by astrocytes in the ischaemic human brain

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Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion

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Characterization of the yeast transcriptome

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Gene expression profiles in normal and cancer cells

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A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes

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The significance of digital gene expression profiles

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Molecular analyses of metallothionein gene regulation.

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Recent excitement regarding metallothionein

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Zinc and brain injury

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Activation of nuclear factor kappaB: potential role in metallothionein-mediated mitogenic response.

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Differences in the cerebrovascular anatomy of C57black/6 and SV129 mice

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The elusive function of metallothioneins

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12 December 2020

Metallothionein-overexpressing neonatal mouse cardiomyocytes are resistant to H2O2 toxicity

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12 December 2020

10.1523/JNEUROSCI.22-14-05879.2002

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757922&resulttype=core&format=json

12 May 2020

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12 May 2020

PubMed publication ID

12122050

1 reference