Transcriptional activation and increase in expression of Alzheimer's beta-amyloid precursor protein gene is mediated by TGF-beta in normal human astrocytes. (Q48559540)

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scientific article published in July 2002

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English	Transcriptional activation and increase in expression of Alzheimer's beta-amyloid precursor protein gene is mediated by TGF-beta in normal human astrocytes.	scientific article published in July 2002

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scholarly article

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

Transcriptional activation and increase in expression of Alzheimer's beta-amyloid precursor protein gene is mediated by TGF-beta in normal human astrocytes. (English)

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

Alzheimer's disease

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human astrocyte

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author name string

Teralee Burton

1

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

Binhua Liang

2

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

Alex Dibrov

3

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

Francis Amara

4

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

language of work or name

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publication date

1 July 2002

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

Biochemical and Biophysical Research Communications

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

295

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

3

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http://europepmc.org/abstract/MED/12099697

702-712

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Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

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Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

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TGF-beta(1), regulation of alzheimer amyloid precursor protein mRNA expression in a normal human astrocyte cell line: mRNA stabilization

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The promoter activity of the gene encoding Alzheimer β-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences

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DNA binding and regulatory effects of transcription factors SP1 and USF at the rat amyloid precursor protein gene promoter

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The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation

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Expression of beta amyloid protein precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR.

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Extension of the life-span of human endothelial cells by an interleukin-1 alpha antisense oligomer

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Cerebral changes and cerebrospinal fluid beta-amyloid in Alzheimer's disease: a study with quantitative magnetic resonance imaging.

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Constitutive NF-kappa B activity in neurons

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Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons

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Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

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The molecular pathology of Alzheimer's disease

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Glial cytokines in Alzheimer's disease: review and pathogenic implications

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Transforming growth factor beta mediates increase of mature transmembrane amyloid precursor protein in microglial cells

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7 January 2021

Transcriptional activation of Alzheimer's beta-amyloid precursor protein gene by stress

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Transcriptional inhibition of the beta-amyloid precursor protein by interferon-gamma.

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7 January 2021

The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter

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Structural features of the 5' upstream regulatory region of the gene encoding rat amyloid precursor protein.

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Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

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Overlapping binding sites of two different transcription factors in the promoter of the human gene for the Alzheimer amyloid precursor protein.

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Effects of transforming growth factor-beta (isoforms 1-3) on amyloid-beta deposition, inflammation, and cell targeting in organotypic hippocampal slice cultures.

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Differential effects of transforming growth factor-beta(s) and glial cell line-derived neurotrophic factor on gene expression of presenilin-1 in human post-mitotic neurons and astrocytes

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Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice

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TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

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Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

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7 January 2021

Identifiers

10.1016/S0006-291X(02)00724-6

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12099697

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