Activin has direct long-range signalling activity and can form a concentration gradient by diffusion. (Q48568112)

12 February 2018

title

Activin has direct long-range signalling activity and can form a concentration gradient by diffusion. (English)

1 reference

12 February 2018

author name string

McDowell N

1

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12 February 2018

Zorn AM

2

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12 February 2018

Crease DJ

3

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12 February 2018

Gurdon JB

4

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12 February 2018

language of work or name

English

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publication date

1 September 1997

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12 February 2018

number of pages

11

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inferred from page(s)

published in

Current Biology

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12 February 2018

volume

7

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12 February 2018

issue

9

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12 February 2018

page(s)

671-681

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12 February 2018

Pattern formation: regional specification in the early C. elegans embryo.

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Presence of activin (erythroid differentiation factor) in unfertilized eggs and blastulae of Xenopus laevis

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Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures

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Identification of activins A, AB, and B and follistatin proteins in Xenopus embryos.

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Activin signalling has a necessary function in Xenopus early development.

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A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

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Disruption of mesoderm and axis formation in fish by ectopic expression of activin variants: the role of maternal activin.

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Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

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Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm.

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Direct and continuous assessment by cells of their position in a morphogen gradient.

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Signalling by TGF-beta family members: short-range effects of Xnr-2 and BMP-4 contrast with the long-range effects of activin.

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Direct and long-range action of a DPP morphogen gradient.

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Identifiers

DOI

1 reference

12 February 2018

PubMed ID

9285724

1 reference

12 February 2018