Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate. (Q48592383)

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19 January 2020

title

Alpha5GABAA receptors mediate the amnestic but not sedative-hypnotic effects of the general anesthetic etomidate (English)

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19 January 2020

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Victor Y Cheng

1

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19 January 2020

Loren J Martin

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19 January 2020

Erin M Elliott

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19 January 2020

John H Kim

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19 January 2020

Howard T J Mount

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19 January 2020

Franco A Taverna

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19 January 2020

John C Roder

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19 January 2020

John F Macdonald

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19 January 2020

Amit Bhambri

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19 January 2020

Neil Collinson

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19 January 2020

Keith A Wafford

11

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19 January 2020

Beverley A Orser

12

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19 January 2020

language of work or name

English

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publication date

1 April 2006

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19 January 2020

published in

Journal of Neuroscience

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19 January 2020

volume

26

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19 January 2020

issue

14

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19 January 2020

page(s)

3713-3720

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Autoradiographic localization of alpha5 subunit-containing GABAA receptors in rat brain

19 January 2020

cites work

1 reference

12 December 2020

Awareness during anaesthesia: a prospective case study

1 reference

12 December 2020

Expression of GABA(A) receptor alpha5 subunit-like immunoreactivity in human hippocampus

1 reference

12 December 2020

Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons.

1 reference

12 December 2020

A simple and efficient high-performance liquid chromatographic assay for etomidate in plasma.

1 reference

12 December 2020

Association between GABA-A receptor alpha 5 subunit gene locus and schizophrenia of a later age of onset

1 reference

12 December 2020

GABA-A receptor beta3 and alpha5 subunit gene cluster on chromosome 15q11-q13 and bipolar disorder: a genetic association study

1 reference

12 December 2020

Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors

1 reference

12 December 2020

Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the alpha 5 subunit of the GABAA receptor.

1 reference

12 December 2020

The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway

1 reference

12 December 2020

General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit.

1 reference

12 December 2020

Tonically activated GABAA receptors in hippocampal neurons are high-affinity, low-conductance sensors for extracellular GABA

1 reference

12 December 2020

Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release.

1 reference

12 December 2020

The memory effects of general anesthesia persist for weeks in young and aged rats

1 reference

12 December 2020

Identification of a Novel, Selective GABAAα5 Receptor Inverse Agonist Which Enhances Cognition

1 reference

12 December 2020

Mechanisms of actions of inhaled anesthetics

1 reference

12 December 2020

Downregulation of the alpha5 subunit of the GABA(A) receptor in the pilocarpine model of temporal lobe epilepsy.

1 reference

12 December 2020

Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.

1 reference

12 December 2020

Effects of isoflurane and nitrous oxide in subanesthetic concentrations on memory and responsiveness in volunteers

1 reference

12 December 2020

Long-term impairment of acquisition of a spatial memory task following isoflurane-nitrous oxide anesthesia in rats

1 reference

12 December 2020

Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors

1 reference

12 December 2020

Tonically active GABA A receptors: modulating gain and maintaining the tone.

1 reference

12 December 2020

Molecular and neuronal substrates for general anaesthetics

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12 December 2020

The incidence of awareness during anesthesia: a multicenter United States study

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12 December 2020

Determination of diffusion and partition coefficients of propofol in rat brain tissue: implications for studies of drug action in vitro.

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12 December 2020

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12 December 2020

Selective enhancement of tonic GABAergic inhibition in murine hippocampal neurons by low concentrations of the volatile anesthetic isoflurane.

1 reference

12 December 2020

Emerging molecular mechanisms of general anesthetic action.

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12 December 2020

Perpetual inhibitory activity in mammalian brain slices generated by spontaneous GABA release

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12 December 2020

Volatile general anaesthetics activate a novel neuronal K+ current

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12 December 2020

Regulation of N-methyl-D-aspartate receptors revealed by intracellular dialysis of murine neurones in culture

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12 December 2020

Conditioned and unconditional components of post-shock freezing.

1 reference

12 December 2020

Expression and properties of recombinant alpha 1 beta 2 gamma 2 and alpha 5 beta 2 gamma 2 forms of the rat GABAA receptor

1 reference

12 December 2020

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

12 December 2020

Hypothesis: inhaled anesthetics produce immobility and amnesia by different mechanisms at different sites

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12 December 2020

Modulation of long-term potentiation in CA1 region of mouse hippocampal brain slices by GABAA receptor benzodiazepine site ligands

1 reference

12 December 2020

Identification of the Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate-type glutamate receptor

1 reference

12 December 2020

Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction

1 reference

12 December 2020

10.1523/JNEUROSCI.5024-05.2006

Identifiers

DOI

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release_j4qqkaufljg5jdtniybupsmqgy

19 January 2020

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24 November 2022

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16597725%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

16597725

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